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基于磁控破裂机制的控释药物用核/单晶壳纳米球。

Core/Single-Crystal-Shell Nanospheres for Controlled Drug Release via a Magnetically Triggered Rupturing Mechanism.

机构信息

Department of Materials Sciences and Engineering National Chiao Tung University Hsinchu 300 (Taiwan).

出版信息

Adv Mater. 2008 Jul 17;20(14):2690-5. doi: 10.1002/adma.200800193. Epub 2008 Jun 2.

DOI:10.1002/adma.200800193
PMID:25213891
Abstract

Core/single-crystal-shell nanospheres are constructed from a poly-(N-vinyl- 2-pyrrolidone) (PVP)-modified silica core with an outer layer of single-crystal iron oxide shell. The nanospheres show outstanding release-and-zero-release characteristics via the addition and removal, respectively, of an external high-frequency magnetic field.

摘要

核/单晶壳纳米球由聚（N-乙烯基-2-吡咯烷酮）（PVP）修饰的二氧化硅核与单晶氧化铁壳组成。通过分别添加和去除外部高频磁场，纳米球表现出优异的释放和零释放特性。

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