Droege Marcus, Marsh Wallace A, Alvarez Goar N, Hunter Tracy S
College of Pharmacy, Nova Southeastern University . Ft. Lauderdale, FL ( USA ).
Pharm Pract (Granada). 2006 Oct;4(4):179-82. doi: 10.4321/s1885-642x2006000400005.
Ethnicity is an important risk factor for the development of osteoporosis. Non-Hispanic white or Asian women are commonly considered at higher risk than other ethnicities. Hispanics in the U.S. are of Mexican, Caribbean, Central American, or South American descent. Conclusive data on the relative risk of osteoporosis in Hispanic women based upon heritage within the Hispanic population are not available.
To investigate whether Hispanic white women are at a significantly lower risk than non- Hispanic whites for the development of osteoporosis.
Cross-sectional study.
Community health screenings.
Hispanic and non-Hispanic white women.
Bone density measurements of the non-dominant heel. Descriptive statistics and inferential statistics including regression analyses were performed using SPSS 14.0.
T scores.
Overall, measurements were obtained from 352 women (209 Hispanic & 143 non-Hispanic white) ranging in age from 55-97 years old. The mean T score obtained for Hispanic women was - 1.194 and -1.280 for non-Hispanic white women. The correlation between the obtained T score and age was negative (r = -0.36, p<0.01), reflecting bone loss with increasing age. Regression analysis using age and ethnicity showed that ethnicity was a non-significant contributor to the best-fit regression line (t=0.60, p=0.55).
This study indicates that Hispanic white women may be at comparable risk of developing osteoporosis as non-Hispanic white women.
种族是骨质疏松症发病的一个重要风险因素。非西班牙裔白人或亚洲女性通常被认为比其他种族的风险更高。美国的西班牙裔有墨西哥、加勒比、中美洲或南美洲血统。关于西班牙裔女性基于其在西班牙裔人群中的血统患骨质疏松症的相对风险的确定性数据尚不明确。
调查西班牙裔白人女性患骨质疏松症的风险是否显著低于非西班牙裔白人女性。
横断面研究。
社区健康筛查。
西班牙裔和非西班牙裔白人女性。
对非优势足跟进行骨密度测量。使用SPSS 14.0进行描述性统计和包括回归分析在内的推断性统计。
T值。
总体而言,对352名年龄在55 - 97岁之间的女性(209名西班牙裔和143名非西班牙裔白人)进行了测量。西班牙裔女性获得的平均T值为 -1.194,非西班牙裔白人女性为 -1.280。获得的T值与年龄之间的相关性为负(r = -0.36,p<0.01),反映出随着年龄增长骨质流失。使用年龄和种族进行的回归分析表明,种族对最佳拟合回归线的贡献不显著(t = 0.60,p = 0.55)。
本研究表明,西班牙裔白人女性患骨质疏松症的风险可能与非西班牙裔白人女性相当。