Siris E, Miller P, Barrett-Connor E, Abbott T, Sherwood L, Berger M
Columbia University, College of Physicians and Surgeons, New York, New York, USA.
Osteoporos Int. 1998;8 Suppl 1:S62-9.
NORA is an observational registry of postmenopausal US women with periodic collection of event and treatment data that will create a database including several hundred thousand subjects. It will utilize peripheral and central measurements of bone density and relate these to other risk factors, treatment patterns, and the natural history of osteoporosis. Initiated in the fall of 1997, the registry will be open to women throughout the United States who agree to complete baseline and on-going surveys. The database created by NORA will provide a resource that is unmatched in size and scope in the medical field and will allow for future research in a number of areas including patient outcomes, types of follow-up employed in clinical practice, diagnostic cost modelling, and osteoporosis therapy use (type, patient compliance, persistence and satisfaction). In addition, upon approval by the Steering Committee, women enrolled in the registry may be randomly selected to receive additional educational materials or questionnaires on a variety of topics of interest to specific researchers.
NORA是一项针对美国绝经后女性的观察性登记研究，定期收集事件和治疗数据，将创建一个包含几十万受试者的数据库。它将利用外周和中心骨密度测量，并将这些与其他风险因素、治疗模式以及骨质疏松症的自然病史相关联。该登记研究于1997年秋季启动，将对全美国同意完成基线调查和持续调查的女性开放。NORA创建的数据库将提供一个在医学领域规模和范围无与伦比的资源，并将允许在包括患者结局、临床实践中采用的随访类型、诊断成本建模以及骨质疏松症治疗使用（类型、患者依从性、持续性和满意度）等多个领域进行未来研究。此外，经指导委员会批准，登记研究中的女性可能会被随机选中，以接收针对特定研究人员感兴趣的各种主题的额外教育材料或问卷。
