Tahaei Ali Akbar, Ashayeri Hassan, Pourbakht Akram, Kamali Mohammad
Department of Audiology, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran 15459-13187, Iran.
Department of Basic Sciences in Rehabilitation, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran 15459-13187, Iran ; Rehabilitation Research Center, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran 15459-13187, Iran.
Scientifica (Cairo). 2014;2014:328646. doi: 10.1155/2014/328646. Epub 2014 Aug 19.
Auditory processing deficits have been hypothesized as an underlying mechanism for stuttering. Previous studies have demonstrated abnormal responses in subjects with persistent developmental stuttering (PDS) at the higher level of the central auditory system using speech stimuli. Recently, the potential usefulness of speech evoked auditory brainstem responses in central auditory processing disorders has been emphasized. The current study used the speech evoked ABR to investigate the hypothesis that subjects with PDS have specific auditory perceptual dysfunction. Objectives. To determine whether brainstem responses to speech stimuli differ between PDS subjects and normal fluent speakers. Methods. Twenty-five subjects with PDS participated in this study. The speech-ABRs were elicited by the 5-formant synthesized syllable/da/, with duration of 40 ms. Results. There were significant group differences for the onset and offset transient peaks. Subjects with PDS had longer latencies for the onset and offset peaks relative to the control group. Conclusions. Subjects with PDS showed a deficient neural timing in the early stages of the auditory pathway consistent with temporal processing deficits and their abnormal timing may underlie to their disfluency.
听觉加工缺陷被认为是口吃的一种潜在机制。以往的研究表明，使用言语刺激时，持续性发育性口吃（PDS）患者在中枢听觉系统的较高水平存在异常反应。最近，言语诱发听觉脑干反应在中枢听觉加工障碍中的潜在作用受到了重视。本研究使用言语诱发听觉脑干反应来探究PDS患者存在特定听觉感知功能障碍这一假设。目的。确定PDS患者与正常流利说话者之间对言语刺激的脑干反应是否存在差异。方法。25名PDS患者参与了本研究。言语听觉脑干反应由时长40毫秒的5共振峰合成音节/da/诱发。结果。起始和结束瞬态峰值存在显著的组间差异。与对照组相比，PDS患者起始和结束峰值的潜伏期更长。结论。PDS患者在听觉通路的早期阶段表现出神经时间处理缺陷，这与时间加工缺陷一致，且他们异常的时间处理可能是其言语不流畅的基础。
