Goldich Yakov, Cooper Michael, Barkana Yaniv, Tovbin Josef, Lee Ovadia Karin, Avni Isaac, Zadok David
From the Department of Ophthalmology (Goldich, Cooper, Barkana, Avni, Zadok) and the Department of Obstetrics & Gynaecology (Tovbin, Ovadia), Assaf Harofeh Medical Center, Zerifin, Israel; the Department of Ophthalmology (Goldich), Toronto Western Hospital, Ontario, Canada.
From the Department of Ophthalmology (Goldich, Cooper, Barkana, Avni, Zadok) and the Department of Obstetrics & Gynaecology (Tovbin, Ovadia), Assaf Harofeh Medical Center, Zerifin, Israel; the Department of Ophthalmology (Goldich), Toronto Western Hospital, Ontario, Canada.
J Cataract Refract Surg. 2014 Nov;40(11):1868-71. doi: 10.1016/j.jcrs.2014.02.042. Epub 2014 Sep 10.
To evaluate the changes occurring in the cornea, anterior segment anatomy, and intraocular pressure (IOP) in pregnant women.
Department of Ophthalmology, Assaf Harofeh Medical Center, Zerifin, Israel.
Prospective single-center comparative study.
The Ocular Response Analyzer dynamic bidirectional applanation device and the Pentacam HR Scheimpflug imaging system were used to obtain data on the anterior eye segments of healthy pregnant and nonpregnant women.
Sixty pregnant and 60 nonpregnant women were enrolled. The Goldmann-correlated IOP and corneal-compensated IOP were significantly lower in the pregnant group (mean 10.96 mm Hg versus 12.97 mm Hg, P<.001; and 10.97 mm Hg versus 13.16 mm Hg, P<.001, respectively). The corneal front steep keratometry value was statistically significantly higher in the pregnant group (44.81 diopters [D] versus 44.1 D, P=.039). No significant difference was found in corneal hysteresis, the corneal resistance factor, corneal posterior curvature, central corneal thickness and volume, anterior chamber depth and volume, or iridocorneal angle.
Pregnancy was associated with greater corneal curvature and lower IOP. Further studies should be performed to learn whether these alterations result from changes in corneal biomechanical properties during pregnancy.
No author has a financial or proprietary interest in any material or method mentioned.
评估孕妇角膜、眼前节解剖结构及眼压（IOP）的变化。
以色列泽里芬阿萨夫·哈罗费医疗中心眼科。
前瞻性单中心对照研究。
使用眼反应分析仪动态双向压平装置和Pentacam HR Scheimpflug成像系统获取健康孕妇和非孕妇眼前节的数据。
纳入60名孕妇和60名非孕妇。孕妇组的Goldmann相关眼压和角膜补偿眼压显著较低（分别为平均10.96 mmHg对12.97 mmHg，P<0.001；以及10.97 mmHg对13.16 mmHg，P<0.001）。孕妇组角膜前表面陡峭角膜曲率计值在统计学上显著更高（44.81屈光度[D]对44.1 D，P = 0.039）。在角膜滞后、角膜阻力因子、角膜后曲率、中央角膜厚度和体积、前房深度和体积或虹膜角膜角方面未发现显著差异。
妊娠与更大的角膜曲率和更低的眼压相关。应进行进一步研究以了解这些改变是否由妊娠期间角膜生物力学特性的变化引起。
没有作者对文中提及的任何材料或方法拥有财务或专利权益。
