Milewsky F, Fassbender T, Würschmidt F, Beck-Bornholdt H P
Institute of Biophysics and Radiobiology, University of Hamburg, FRG.
Strahlenther Onkol. 1990 Sep;166(9):588-90.
A simple experimental technique for interstitial iridium-192 high dose-rate afterloading is described which allows to perform experimental brachytherapy on a rat tumor model. To illustrate the possibilities and limitations of the technique, rhabdomyosarcoma R1H of the rat were subjected to a combined brachy- and teletherapy treatment applying a total dose of 60 Gy in fractions of 2 Gy. The results show that the surgical procedure had no influence on tumor response. However, would healing was considerably disturbed in animals which received afterloading treatment.
描述了一种用于间质铱 - 192高剂量率后装的简单实验技术，该技术可在大鼠肿瘤模型上进行实验性近距离放射治疗。为了说明该技术的可能性和局限性，对大鼠的横纹肌肉瘤R1H进行了近距离放疗和远距离放疗相结合的治疗，总剂量为60 Gy，每次2 Gy。结果表明，手术操作对肿瘤反应没有影响。然而，接受后装治疗的动物伤口愈合受到了相当大的干扰。
