Pauné J, Queiros A, Quevedo L, Neves H, Lopes-Ferreira D, González-Méijome J M
Centro Medico Teknon, Barcelona, Spain.
Clinical & Experimental Optometry Research Lab (CEORLab), Center of Physics, University of Minho, Braga, Portugal.
Cont Lens Anterior Eye. 2014 Dec;37(6):455-60. doi: 10.1016/j.clae.2014.08.001. Epub 2014 Sep 11.
To evaluate the performance of two experimental contact lenses (CL) designed to induce relative peripheral myopic defocus in myopic eyes.
Ten right eyes of 10 subjects were fitted with three different CL: a soft experimental lens (ExpSCL), a rigid gas permeable experimental lens (ExpRGP) and a standard RGP lens made of the same material (StdRGP). Central and peripheral refraction was measured using a Grand Seiko open-field autorefractometer across the central 60° of the horizontal visual field. Ocular aberrations were measured with a Hartman-Shack aberrometer, and monocular contrast sensitivity function (CSF) was measured with a VCTS6500 without and with the three contact lenses.
Both experimental lenses were able to increase significantly the relative peripheral myopic defocus up to -0.50 D in the nasal field and -1.00 D in the temporal field (p<0.05). The ExpRGP induced a significantly higher myopic defocus in the temporal field compared to the ExpSCL. ExpSCL induced significantly lower levels of Spherical-like HOA than ExpRGP for the 5mm pupil size (p<0.05). Both experimental lenses kept CSF within normal limits without any statistically significant change from baseline (p>0.05).
RGP lens design seems to be more effective to induce a significant myopic change in the relative peripheral refractive error. Both lenses preserve a good visual performance. The worsened optical quality observed in ExpRGP was due to an increased coma-like and spherical-like HOA. However, no impact on the visual quality as measured by CSF was observed.
评估两种旨在诱导近视眼中相对周边近视性离焦的实验性隐形眼镜(CL)的性能。
为10名受试者的10只右眼佩戴三种不同的隐形眼镜:软性实验镜片(ExpSCL)、硬性透气性实验镜片(ExpRGP)和由相同材料制成的标准RGP镜片(StdRGP)。使用Grand Seiko开放式视野自动验光仪在水平视野的中央60°范围内测量中央和周边屈光。用Hartman-Shack像差仪测量眼像差,并用VCTS6500在不佩戴和佩戴三种隐形眼镜的情况下测量单眼对比敏感度函数(CSF)。
两种实验镜片均能在鼻侧视野显著增加相对周边近视性离焦至-0.5D,在颞侧视野增加至-1.00D(p<0.05)。与ExpSCL相比,ExpRGP在颞侧视野诱导出显著更高的近视性离焦。对于5mm瞳孔大小,ExpSCL诱导的类球差水平明显低于ExpRGP(p<0.05)。两种实验镜片均使CSF保持在正常范围内,与基线相比无统计学显著变化(p>0.05)。
RGP镜片设计似乎更有效地诱导相对周边屈光不正发生显著的近视性变化。两种镜片均保持良好的视觉性能。在ExpRGP中观察到的光学质量恶化是由于类彗差和类球差增加。然而,未观察到对CSF测量的视觉质量有影响。