Division of General Dermatology, Medical University of Graz, Graz, Austria.
Department of Pathology, Maastricht University Medical Center, Maastricht, The Netherlands.
J Invest Dermatol. 2014 Oct;134(10):2491-2493. doi: 10.1038/jid.2014.233.
Adult skin stem cells do not protect their genome by asymmetric chromosome segregation; thus, they are prone to accumulating oncogenic mutations.
成人皮肤干细胞不会通过不对称的染色体分离来保护其基因组;因此,它们容易积累致癌突变。