Verma Rajesh, Sahu Ritesh, Holla Vikram
Neurology, King George Medical University, Lucknow, UP, India.
Neurology, King George Medical University, Lucknow, UP, India.
J Neurol Sci. 2014 Nov 15;346(1-2):26-34. doi: 10.1016/j.jns.2014.08.044. Epub 2014 Sep 6.
Dengue is a common arboviral infection in tropical and sub-tropical areas of the world transmitted by Aedes mosquitoes and caused by infection with one of the 4 serotypes of dengue virus. Neurologic manifestations are increasingly recognised but the exact incidence is unknown. Dengue infection has a wide spectrum of neurological complications such as encephalitis, myositis, myelitis, Guillain-Barré syndrome (GBS) and mononeuropathies. Encephalopathy is the most common reported complication. In endemic regions, dengue infection should be considered as one of the aetiologies of encephalitis. Even for other neurological syndromes like myelitis, myositis, GBS etc., dengue infection should be kept in differential diagnosis and should be ruled out especially so in endemic countries during dengue outbreaks and in cases where the aetiology is uncertain. A high degree of suspicion in endemic areas can help in picking up more cases thereby helping in understanding the true extent of neurological complications in dengue fever. Also knowledge regarding the various neurological complications helps in looking for the warning signs and early diagnosis thereby improving patient outcome.
登革热是一种在世界热带和亚热带地区常见的虫媒病毒感染，由伊蚊传播，由感染4种登革病毒血清型之一引起。神经系统表现越来越受到认可，但确切发病率尚不清楚。登革热感染有广泛的神经系统并发症，如脑炎、肌炎、脊髓炎、格林-巴利综合征（GBS）和单神经病。脑病是最常见的报告并发症。在流行地区，登革热感染应被视为脑炎的病因之一。即使对于其他神经系统综合征，如脊髓炎、肌炎、GBS等，登革热感染也应进行鉴别诊断，尤其在登革热流行期间的流行国家以及病因不明的病例中应排除该病因。在流行地区保持高度怀疑有助于发现更多病例，从而有助于了解登革热神经系统并发症的真实程度。此外，有关各种神经系统并发症的知识有助于寻找警示信号和早期诊断，从而改善患者预后。
