Naik Soham N
Radiodiagnosis, Sir Takhtasinhji General Hospital, Bhavnagar, IND.
Cureus. 2024 Nov 30;16(11):e74835. doi: 10.7759/cureus.74835. eCollection 2024 Nov.
Acute leukoencephalopathy with restricted diffusion (ALERD) is an emerging clinico-radiological syndrome marked by sudden onset encephalopathy and characteristic restricted diffusion in the subcortical white matter on MRI. While typically linked to other viral etiologies, its association with dengue fever is not well known and is rarely documented in the literature. In this report, we describe a rare case of ALERD associated with dengue fever in a young patient, emphasizing clinical features, neuroimaging findings, management, and outcome. This case reinforces the need to consider dengue as a potential etiologic factor for ALERD in endemic regions and highlights the importance of timely intervention for improving patient outcomes.
伴弥散受限的急性白质脑病(ALERD)是一种新出现的临床-放射学综合征,其特征为突然起病的脑病以及MRI显示皮质下白质具有特征性的弥散受限。虽然它通常与其他病毒病因有关,但其与登革热的关联尚不为人所知,且在文献中鲜有记载。在本报告中,我们描述了一名年轻患者中与登革热相关的罕见ALERD病例,重点介绍了临床特征、神经影像学表现、治疗及预后。该病例强调了在流行地区将登革热视为ALERD潜在病因的必要性,并突出了及时干预对改善患者预后的重要性。