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以急性局限性扩散性白质脑病为表现的登革热罕见病例报告

A Rare Case Report of Dengue Fever Presenting With Acute Leukoencephalopathy With Restricted Diffusion.

作者信息

Naik Soham N

机构信息

Radiodiagnosis, Sir Takhtasinhji General Hospital, Bhavnagar, IND.

出版信息

Cureus. 2024 Nov 30;16(11):e74835. doi: 10.7759/cureus.74835. eCollection 2024 Nov.

DOI:10.7759/cureus.74835
PMID:39737281
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11684464/
Abstract

Acute leukoencephalopathy with restricted diffusion (ALERD) is an emerging clinico-radiological syndrome marked by sudden onset encephalopathy and characteristic restricted diffusion in the subcortical white matter on MRI. While typically linked to other viral etiologies, its association with dengue fever is not well known and is rarely documented in the literature. In this report, we describe a rare case of ALERD associated with dengue fever in a young patient, emphasizing clinical features, neuroimaging findings, management, and outcome. This case reinforces the need to consider dengue as a potential etiologic factor for ALERD in endemic regions and highlights the importance of timely intervention for improving patient outcomes.

摘要

伴弥散受限的急性白质脑病(ALERD)是一种新出现的临床-放射学综合征,其特征为突然起病的脑病以及MRI显示皮质下白质具有特征性的弥散受限。虽然它通常与其他病毒病因有关,但其与登革热的关联尚不为人所知,且在文献中鲜有记载。在本报告中,我们描述了一名年轻患者中与登革热相关的罕见ALERD病例,重点介绍了临床特征、神经影像学表现、治疗及预后。该病例强调了在流行地区将登革热视为ALERD潜在病因的必要性,并突出了及时干预对改善患者预后的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83b3/11684464/830e3ded3b2f/cureus-0016-00000074835-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83b3/11684464/447d2a8dcb45/cureus-0016-00000074835-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83b3/11684464/323287d1c7f6/cureus-0016-00000074835-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83b3/11684464/b9f02e9f3fcc/cureus-0016-00000074835-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83b3/11684464/830e3ded3b2f/cureus-0016-00000074835-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83b3/11684464/447d2a8dcb45/cureus-0016-00000074835-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83b3/11684464/323287d1c7f6/cureus-0016-00000074835-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83b3/11684464/b9f02e9f3fcc/cureus-0016-00000074835-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83b3/11684464/830e3ded3b2f/cureus-0016-00000074835-i04.jpg

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本文引用的文献

1
Acute Necrotizing Encephalopathy of Childhood: A Rare Neurological Manifestation of Dengue.儿童急性坏死性脑病:登革热的一种罕见神经表现。
Ann Indian Acad Neurol. 2021 Sep-Oct;24(5):828-831. doi: 10.4103/aian.AIAN_809_20. Epub 2021 Apr 17.
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The spectrum of acute leukoencephalopathy with restricted diffusion (ALERD): A case series and review of literature.急性白细胞脑白质病伴弥散受限的谱:病例系列和文献复习。
Eur J Paediatr Neurol. 2021 Jul;33:86-93. doi: 10.1016/j.ejpn.2021.05.017. Epub 2021 Jun 6.
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Acute Leukoencephalopathy with Restricted Diffusion.
伴弥散受限的急性白质脑病
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Neurological manifestations of dengue infection: a review.登革热感染的神经系统表现:综述
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Differences of clinical manifestations according to the patterns of brain lesions in acute encephalopathy with reduced diffusion in the bilateral hemispheres.双侧半球弥散受限的急性脑病中,根据脑损伤模式的临床表现差异。
AJNR Am J Neuroradiol. 2009 Apr;30(4):825-30. doi: 10.3174/ajnr.A1431. Epub 2009 Jan 8.
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Encephalitis and myelitis associated with dengue viral infection clinical and neuroimaging features.登革病毒感染相关的脑炎和脊髓炎:临床及神经影像学特征
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