Garvey M J, Schaffer C, Schaffer L, Perry P J
Department of Psychiatry, VA Medical Center, Iowa City, IA 52240.
J Affect Disord. 1989 Mar-Jun;16(2-3):159-65. doi: 10.1016/0165-0327(89)90070-0.
Depressed inpatients have a DST non-suppression rate that is several times greater than that of depressed outpatients. To explore what clinical features of depression might explain this difference, 25 depressed inpatients who were DST non-suppressors were compared with 16 DST suppressors, using 70 clinical variables. Those variables that were different between these two groups of inpatients were then used to compare depressed inpatients and outpatients. Three variables that were significantly associated with DST status in depressed inpatients were also found to differentiate between depressed inpatients and depressed outpatients. DST suppression was associated with a family history of alcoholism, with the symptom hypersomnia, and with a younger age at index interview.
抑郁住院患者的地塞米松抑制试验（DST）不抑制率比抑郁门诊患者高出数倍。为探究抑郁症的哪些临床特征可以解释这种差异，使用70项临床变量，对25名DST不抑制的抑郁住院患者与16名DST抑制患者进行了比较。然后，将这两组住院患者之间存在差异的变量用于比较抑郁住院患者和门诊患者。还发现，在抑郁住院患者中与DST状态显著相关的三个变量也能区分抑郁住院患者和抑郁门诊患者。DST抑制与酒精中毒家族史、症状性嗜睡以及首次访谈时年龄较轻有关。
