Sudakov S K
Biull Eksp Biol Med. 1989 Feb;107(2):135-8.
Influence of food intake on hypothalamically induced avoidance reactions have been studied in rabbits. It was shown that first contact with food and beginning of food intake accompany with activation of avoidance reactions. Central action of cholecystokinin-octapeptide, pentagastrin, beta-endorphin and naloxone on avoidance reactions of fed and fasted rabbits before and during food intake was investigated. It was found that injection of cholecystokinin and naloxone, which had a satiated effect, act on avoidance reactions similarly in fed and fasted rabbits. Beta-endorphin inhibits avoidance behavior, and only pentagastrin activates avoidance reactions of fasted but not fed rabbits. It is concerned that influence of feeding motivation may modulate avoidance behavior by participation of endogenous gastrin-like peptide release into the perineuronal area during contact of rabbits with food and beginning of its intake.
对家兔下丘脑诱导的回避反应中食物摄入的影响进行了研究。结果表明，首次接触食物和开始进食伴随着回避反应的激活。研究了胆囊收缩素八肽、五肽胃泌素、β-内啡肽和纳洛酮在进食前和进食期间对喂食和禁食家兔回避反应的中枢作用。发现注射具有饱腹感作用的胆囊收缩素和纳洛酮，对喂食和禁食家兔的回避反应作用相似。β-内啡肽抑制回避行为，只有五肽胃泌素能激活禁食但非喂食家兔的回避反应。有人认为，进食动机的影响可能通过家兔接触食物并开始进食时内源性胃泌素样肽释放到神经周区域来调节回避行为。
