Kamimura Akio, Murata Kengo, Tanaka Yoshiki, Okagawa Tomoki, Matsumoto Hiroshi, Kaiso Kouji, Yoshimoto Makoto
Department of Applied Molecular Bioscience, Graduate School of Medicine, Yamaguchi University, Ube 755-8611 (Japan).
ChemSusChem. 2014 Dec;7(12):3257-9. doi: 10.1002/cssc.201402655. Epub 2014 Sep 15.
Sorbitol was effectively converted to isosorbide by treatment with [TMPA][NTf2 ] in the presence of catalytic amounts of TsOH under microwave heating at 180 °C. The reaction completed within 10 min and isosorbide was isolated to about 60%. Ionic liquids were readily recovered by an extraction treatment and reused several times.
在180℃微波加热条件下，在催化量的对甲苯磺酸存在下，用[三甲基苯基铵][双（三氟甲基磺酰）亚胺]处理，山梨醇有效地转化为异山梨醇。反应在10分钟内完成，异山梨醇的分离产率约为60%。离子液体通过萃取处理很容易回收，并可重复使用几次。
