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高龄老人脆性骨折风险的程度——我们是否满足了他们的需求?纽卡斯尔85岁及以上老人研究。

Magnitude of fragility fracture risk in the very old--are we meeting their needs? The Newcastle 85+ Study.

作者信息

Duncan R, Francis R M, Jagger C, Kingston A, McCloskey E, Collerton J, Robinson L, Kirkwood T B L, Birrell F

机构信息

Institute of Health and Society, Newcastle University, Baddiley-Clark Building, Richardson Road, Newcastle upon Tyne, NE2 4AX, UK,

出版信息

Osteoporos Int. 2015 Jan;26(1):123-30. doi: 10.1007/s00198-014-2837-8. Epub 2014 Sep 16.

Abstract

UNLABELLED

Fractures due to osteoporosis are common in older people. This study assessed the management of osteoporosis in a group of 85-year-olds and found both assessment and current treatment to be suboptimal.

INTRODUCTION

Fragility fractures are a major cause of excess mortality, substantial morbidity, and health and social service expenditure in older people. However, much less is known about fracture risk and its management in the very old, despite this being the fastest growing age group of our population.

METHODS

Cross-sectional analysis of people who reached the age of 85 during the year of 2006 was carried out. Data were gathered by general practice record review (GPRR) and a multidimensional health assessment (MDHA).

RESULTS

Seven hundred thirty-nine individuals were recruited. Mean age was 85.55 years (SD 0.44), and 60.2% were female; 33.7% (n = 249) had experienced one or more fragility fractures (F 45.2% vs M 16.3% p < 0.001); in total, 332 fractures occurred in these 249 individuals. A formal documented diagnosis of osteoporosis occurred in 12.4%, and 38% of individuals had experienced a fall in the last 12 months. When the fracture risk assessment tool (FRAX) and National Osteoporosis Guideline Group (NOGG) guidelines were applied, osteoporosis treatment would be recommended in 35.0%, with a further 26.1% identified as needing bone mineral density (BMD) measurement and 38.9% not requiring treatment or BMD assessment. Women were more likely than men to need treatment (47.4 vs 16.3%, p < 0.001, odds ratio (OR) 4.62 (3.22-5.63)) and measurement of BMD (40.0 vs 5.1%, p < 0.001, OR 12.4 (7.13-21.6)). Of the 259 individuals identified as requiring treatment, only 74 (28.6%) were on adequate osteoporosis treatment.

CONCLUSION

The prevalence of high fracture risk in the very old is much higher than the documented diagnosis of osteoporosis or the use of adequate treatments.

摘要

未标注

骨质疏松导致的骨折在老年人中很常见。本研究评估了一组85岁老人的骨质疏松管理情况,发现评估和当前治疗均未达到最佳水平。

引言

脆性骨折是老年人超额死亡率、严重发病率以及健康和社会服务支出的主要原因。然而,尽管高龄人群是我们人口中增长最快的年龄组,但对于这个年龄段的骨折风险及其管理却知之甚少。

方法

对2006年年满85岁的人群进行横断面分析。数据通过全科医疗记录回顾(GPRR)和多维健康评估(MDHA)收集。

结果

招募了739人。平均年龄为85.55岁(标准差0.44),女性占60.2%;33.7%(n = 249)曾经历过一次或多次脆性骨折(女性45.2%,男性16.3%,p < 0.001);在这249人中总共发生了332处骨折。正式记录的骨质疏松诊断为12.4%,38%的人在过去12个月内曾跌倒。当应用骨折风险评估工具(FRAX)和国家骨质疏松指南组(NOGG)指南时,35.0%的人会被建议进行骨质疏松治疗,另有26.1%的人被确定需要测量骨密度(BMD),38.9%的人不需要治疗或BMD评估。女性比男性更有可能需要治疗(47.4%对16.3%,p < 0.001,优势比(OR)4.62(3.22 - 5.63))和测量BMD(40.0%对5.1%,p < 0.001,OR 12.4(7.13 - 21.6))。在确定需要治疗的259人中,只有74人(28.6%)接受了充分的骨质疏松治疗。

结论

高龄人群中高骨折风险的患病率远高于记录在案的骨质疏松诊断率或充分治疗的使用率。

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