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强直性脊柱炎患者脊柱创伤的回顾性分析:印度人群的描述性研究

Retrospective analysis of spinal trauma in patients with ankylosing spondylitis: a descriptive study in Indian population.

作者信息

Mahajan R, Chhabra H S, Srivastava A, Venkatesh R, Kanagaraju V, Kaul R, Tandon V, Nanda A, Sangondimath G, Patel N

机构信息

Spine Services, Indian Spinal Injuries Centre, New Delhi, India.

出版信息

Spinal Cord. 2015 May;53(5):353-7. doi: 10.1038/sc.2014.150. Epub 2014 Sep 16.

Abstract

OBJECTIVE

This study aims to understand the demographics, mode of trauma, hospital stay, complications, neurological improvement, mortality and expenditure incurred by Indian patients with spinal trauma and ankylosing spondylitis (AS).

METHODS

Retrospective analysis of the patient data admitted to a tertiary referral hospital from 2008 to 2013 with the diagnosis of AS and spinal trauma was carried out. The variables studied were demographics, mode of trauma, neurological status, neurological improvement, involved vertebral level, duration of hospital stay, comorbid factors, expenditure and complications during the stay.

RESULTS

Forty-six patients with diagnosis of AS with spine trauma were admitted over the last 5 years with a total of 52 fractures. All were male patients; 58.6% had injury because of trivial trauma and 78.2% patients presented with neurological injury. C5 C6, C6 C7, C7 D1 and D12 were the most common injured level. Fractures through intervertebral disc were most common in cervical spine. Of the patients, 52.7% had shown neurological improvement of at least grade 1(AIS). Mean expenditure of patient admitted with spinal cord injury (SCI) with AS is 7957 USD (United States dollar), which is around five times the per capita income in India (as per year 2013).

CONCLUSION

Males with AS are much more prone to spinal fractures than females and its incidence may be higher than previously reported. Domestic falls are the most common mechanism of spinal trauma in this population. High velocity injuries are associated with complete SCI. The study reinforces the need for development of subsidized spinal care services for SCI management.

摘要

目的

本研究旨在了解印度脊柱创伤和强直性脊柱炎(AS)患者的人口统计学特征、创伤方式、住院时间、并发症、神经功能改善情况、死亡率及费用支出。

方法

对2008年至2013年入住一家三级转诊医院且诊断为AS合并脊柱创伤的患者数据进行回顾性分析。研究的变量包括人口统计学特征、创伤方式、神经功能状态、神经功能改善情况、受累椎体节段、住院时间、合并因素、费用支出及住院期间的并发症。

结果

在过去5年中,共收治了46例诊断为AS合并脊柱创伤的患者,共有52处骨折。所有患者均为男性;58.6%的患者因轻微创伤受伤,78.2%的患者伴有神经损伤。C5 C6、C6 C7、C7 D1和D12是最常见的损伤节段。椎间盘骨折在颈椎最为常见。其中,52.7%的患者神经功能至少改善了1级(美国脊髓损伤协会损伤分级标准)。AS合并脊髓损伤(SCI)患者的平均费用为7957美元,约为印度人均收入(按照2013年)的五倍。

结论

AS男性患者比女性更容易发生脊柱骨折,其发病率可能高于先前报道。家庭跌倒为此类人群脊柱创伤最常见的机制。高速损伤与完全性SCI相关。该研究强化了为SCI管理开发补贴性脊柱护理服务的必要性。

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