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使用陶瓷空间维持装置引导骨增量术。

Guided bone augmentation using a ceramic space-maintaining device.

作者信息

Anderud Jonas, Jimbo Ryo, Abrahamsson Peter, Isaksson Sten G, Adolfsson Erik, Malmström Johan, Kozai Yusuke, Hallmer Fredrik, Wennerberg Ann

机构信息

Department of Prosthodontics, Faculty of Odontology, Malmö University, Malmö, Sweden; Maxillofacial Unit Halmstad, Region Halland, Halmstad, Sweden.

Department of Prosthodontics, Faculty of Odontology, Malmö University, Malmö, Sweden.

出版信息

Oral Surg Oral Med Oral Pathol Oral Radiol. 2014 Nov;118(5):532-8. doi: 10.1016/j.oooo.2014.06.011. Epub 2014 Jul 3.

Abstract

OBJECTIVE

The purpose of this study was to evaluate 3-dimensionally whether vertical bone augmentation can be achieved using a hollow hydroxyapatite space-maintaining device in a rabbit calvarial model. Furthermore, different inner surface topographies, different permeabilities, and different porosities of the ceramic were tested to determine the optimal conditions for bone regeneration.

STUDY DESIGN

A total of 48 hollow domes made of hydroxyapatite in 4 different designs were placed subperiosteally on rabbit skull bone. The rabbits were humanely killed after 12 weeks, and the results were analyzed 3-dimensionally using micro-computed tomography.

RESULTS

The results suggest a larger production of bone volume when using an occlusive, dense hydroxyapatite space-maintaining device with a rough inner surface.

CONCLUSIONS

Hydroxyapatite space-maintaining devices permit new bone formation and osteoconduction within the dome.

摘要

目的

本研究旨在通过兔颅骨模型,三维评估使用中空羟基磷灰石间隙维持装置能否实现垂直骨增量。此外,还测试了陶瓷不同的内表面形貌、不同的渗透性和不同的孔隙率,以确定骨再生的最佳条件。

研究设计

将4种不同设计的共48个由羟基磷灰石制成的中空圆顶置于兔颅骨骨膜下。12周后对兔子实施安乐死,然后使用微型计算机断层扫描进行三维结果分析。

结果

结果表明,使用具有粗糙内表面的封闭、致密羟基磷灰石间隙维持装置时,骨体积生成量更大。

结论

羟基磷灰石间隙维持装置可使圆顶内形成新骨并具有骨传导性。

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