Mansoor Aqil, FCPS, Associate Professor, Department of Anesthesiology (41), College of Medicine, King Saud University, Consultant Anesthetist, King Khalid University Hospital, Riyadh, Saudi Arabia.
Pak J Med Sci. 2014 Sep;30(5):1001-6. doi: 10.12669/pjms.305.4788.
To compare hemodynamic stress response (HDSR) to ET intubation using Glidescope (GLS) and Flexible fiberoptic laryngoscope (FFB).
This prospective randomized comparative study was conducted at King Khalid University Hospital, King Saud University, Riyadh, Saudi Arabia from June 2011 - November 2013. Eighty ASA 1 & 2 patients with normal airway undergoing elective surgical procedure requiring ET intubation were included in the study. Patients were randomly assigned in two groups GLS or FFB. General anesthesia was induced with propofol and fentanyl. Muscle relaxation was achieved with cisatracurium and ET intubation was performed using either GLS or FFB. Noninvasive hemodynamic data was recorded (HR, systolic, diastolic and mean blood pressure) as pre-induction, baseline and after ET intubation at one minute intervals for successive five minutes. End tidal Sevoflurane and CO2 at the time of intubation, need of external neck pressure, time to successful intubation and number of attempts were recorded; and rate pressure product was calculated.
Induction of anesthesia resulted in significant fall in blood pressure in both the groups. ET intubation resulted in similar rise of BP in both groups (for 3-4 minutes) from their baseline values; however the rise was not significantly different from their respective pre-induction values. Time to intubation was longer with FFB compared to GLS however, need for external neck manipulation was more with GLS.
There was no difference in HDSR due to ET intubation using either GLS or FFB in healthy adult patients with normal airway. Rate pressure product remained within the acceptable range.
比较使用 Glidescope(GLS)和纤维光导喉镜(FFB)行气管插管时的血流动力学应激反应(HDSR)。
本前瞻性随机对照研究于 2011 年 6 月至 2013 年 11 月在沙特阿拉伯利雅得的沙特国王大学国王 Khalid 大学医院进行。纳入了 80 例需行气管插管的择期手术的 ASA 1 和 2 级、气道正常的患者。患者随机分为 GLS 或 FFB 两组。全身麻醉诱导采用丙泊酚和芬太尼,顺式阿曲库铵肌松后行气管插管,使用 GLS 或 FFB。在诱导前、基线时和气管插管后 1 分钟内连续记录 5 分钟的非侵入性血流动力学数据(HR、收缩压、舒张压和平均血压)。记录气管插管时的呼气末七氟醚和 CO2、是否需要外部颈部施压、插管成功时间和尝试次数,并计算心率-收缩压乘积。
麻醉诱导导致两组血压均显著下降。气管插管后两组的血压均有类似的升高(3-4 分钟),与基线值相比;但与各自的诱导前值相比,升高无显著差异。FFB 组的插管时间比 GLS 组长,但 GLS 组需要外部颈部操作的次数更多。
在气道正常的健康成年患者中,使用 GLS 或 FFB 行气管插管时,HDSR 无差异。心率-收缩压乘积仍在可接受范围内。