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升主动脉替换术无需体外循环或深低温:“分支优先”技术。

Aortic arch replacement without circulatory arrest or deep hypothermia: the "branch-first" technique.

机构信息

Department of Cardiac Surgery, Austin Hospital, University of Melbourne, Melbourne, Australia.

Department of Cardiac Surgery, Austin Hospital, University of Melbourne, Melbourne, Australia.

出版信息

J Thorac Cardiovasc Surg. 2015 Feb;149(2 Suppl):S76-82. doi: 10.1016/j.jtcvs.2014.07.100. Epub 2014 Aug 10.

Abstract

OBJECTIVE

Although current developments in aortic arch replacement have demonstrated progressively improving mortality, cerebral morbidity remains significant. We describe a "branch-first" technique that avoids circulatory arrest and profound hypothermia, yielding excellent survival and low cerebral morbidity.

METHODS

From September 2005 to February 2014, 64 patients underwent the "branch-first" technique for aortic arch replacement. Each arch branch is individually isolated for a brief period while it is anastomosed to a perfused trifurcation graft. The disconnection-reconnection sequence proceeds from the innominate artery to the left subclavian artery, with uninterrupted perfusion of the heart and viscera. After reconstruction of the debranched arch and ascending aorta, the common stem of the trifurcation graft is anastomosed to the arch graft. In this series, there were 39 male patients, and the mean age was 65 (range, 17-85) years. Twenty-five cases (39.1%) were of urgent/emergency status. Thirty-one patients (48.4%) underwent operation for aortic dissection, and the remaining patients underwent operation for aneurysms. Sixteen patients (25.0%) had previously undergone a cardiac surgical procedure.

RESULTS

There were 2 (3.1%) early mortalities, and 1 patient (1.6%) had a permanent stroke. One patient (1.6%) required mechanical support, and 4 patients (6.3%) required hemofiltration for renal support. Ten patients (15.6%) did not require transfusion of red cells or any other blood product.

CONCLUSIONS

The "branch-first" technique described brings us closer to the goal of arch surgery with cerebral, vital organ, and survival outcomes similar to those we expect from ascending aortic and root procedures.

摘要

目的

尽管当前主动脉弓置换术的发展已显示出死亡率逐渐降低,但脑卒发病率仍居高不下。我们描述了一种“分支优先”技术,该技术避免了循环中断和深度低温,从而获得了良好的生存率和较低的脑卒中发病率。

方法

2005 年 9 月至 2014 年 2 月,64 例患者接受了主动脉弓置换的“分支优先”技术。每个弓分支在与灌注的三分支移植物吻合的短暂时间内被单独隔离。断开-再连接的顺序从无名动脉进行到左锁骨下动脉,心脏和内脏持续灌注。在重建去分支的弓和升主动脉后,三分支移植物的共同主干与弓移植物吻合。在本系列中,有 39 例男性患者,平均年龄为 65(范围 17-85)岁。25 例(39.1%)为紧急/紧急状态。31 例(48.4%)因主动脉夹层而行手术,其余患者因动脉瘤而行手术。16 例(25.0%)曾行心脏外科手术。

结果

有 2 例(3.1%)早期死亡,1 例(1.6%)永久性脑卒中。1 例(1.6%)需要机械支持,4 例(6.3%)需要血液滤过进行肾脏支持。10 例(15.6%)不需要输注红细胞或任何其他血液制品。

结论

所描述的“分支优先”技术使我们更接近具有类似脑、重要器官和生存结果的弓手术目标,这些结果与我们预期的升主动脉和根部手术相似。

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