Tokmak Aytekin, Kokanali Mahmut Kuntay, Guzel Ali Irfan, Kara Aydan, Topcu Hasan Onur, Cavkaytar Sabri
Obstetrics and Gynecology Department, Dr Zekai Tahir Burak Woman's Health Education and Research Hospital, Ankara, Turkey E-mail :
Asian Pac J Cancer Prev. 2014;15(17):7011-4. doi: 10.7314/apjcp.2014.15.17.7011.
The polycystic ovary syndrome is the most common endocrinological disorder of reproductive age women with a prevalence of 5 to 8 %. The most common diagnostic criteria used for polycystic ovary syndrome are oligo- or an-ovulation, clinical and/ or biochemical signs of hyperandrogenism and polycystic ovaries. Hyperandrogenism results in increased estrogen levels and lack of cyclic progesterone due to anovulation and persistent stimulation of the endometrium may lead to endometrial hyperplasia or adenocarcinoma development. In this mini review, we aimed to evaluate the possible relationship between polycystic ovary syndrome and endometrial cancer.
多囊卵巢综合征是育龄女性中最常见的内分泌紊乱疾病，患病率为5%至8%。用于诊断多囊卵巢综合征最常用的标准是排卵稀少或无排卵、高雄激素血症的临床和/或生化体征以及多囊卵巢。高雄激素血症会导致雌激素水平升高，由于无排卵，缺乏周期性孕酮，子宫内膜持续受到刺激可能会导致子宫内膜增生或腺癌的发生。在这篇小型综述中，我们旨在评估多囊卵巢综合征与子宫内膜癌之间可能存在的关系。
