Kim Uh Jin, Kim Hee Kyung, An Joon Hwan, Cho Soo Kyung, Park Kyung-Hwa, Jang Hee-Chang
Department of Infectious Diseases, Chonnam National University Medical School, Gwangju, Korea.
Chonnam Med J. 2014 Aug;50(2):37-44. doi: 10.4068/cmj.2014.50.2.37. Epub 2014 Aug 20.
Carbapenem-resistant Acinetobacter species are increasingly recognized as major nosocomial pathogens, especially in patients with critical illnesses or in intensive care. The ability of these organisms to accumulate diverse mechanisms of resistance limits the available therapeutic agents, makes the infection difficult to treat, and is associated with a greater risk of death. In this review, we provide an update on the epidemiology, resistance mechanisms, infection control measures, treatment, and outcomes of carbapenem-resistant Acinetobacter infections.
耐碳青霉烯类不动杆菌属日益被认为是主要的医院病原体,尤其是在危重病患者或重症监护患者中。这些微生物积累多种耐药机制的能力限制了可用的治疗药物,使感染难以治疗,并与更高的死亡风险相关。在本综述中,我们提供了关于耐碳青霉烯类不动杆菌感染的流行病学、耐药机制、感染控制措施、治疗及结果的最新信息。