Sabudak Temine, Kaya Oktay, Cukurova Elif
a Department of Chemistry , Faculty of Science and Letters, Namik Kemal University , 59860 Tekirdag , Turkey.
Nat Prod Res. 2015;29(4):308-14. doi: 10.1080/14786419.2014.928878. Epub 2014 Sep 18.
A new biflavone, 6,2',3″,5″,4‴-pentahydroxy-3,7″-biflavone, has been isolated from the fruits of Solanum dulcamara L., in addition to two known compounds, β-sitosterol and stigmasterol. Their structures were established on the basis of UV, IR, 1D, 2D NMR and HR-ESI-MS spectroscopic methods. The anti-hyperglycaemic effect of S. dulcamara was investigated using diabetic rats. The anti-hyperglycaemic activity of the fruit extract of S. dulcamara was presented for the first time in this study.
除了两种已知化合物β-谷甾醇和豆甾醇外，还从欧白英果实中分离出一种新的双黄酮，即6,2',3″,5″,4‴-五羟基-3,7″-双黄酮。它们的结构是基于紫外、红外、一维、二维核磁共振和高分辨电喷雾电离质谱光谱法确定的。使用糖尿病大鼠研究了欧白英的抗高血糖作用。本研究首次报道了欧白英果实提取物的抗高血糖活性。
