Sharma R L, Bhat T K, Dhar D N
Regional Research Centre, Indian Veterinary Research Institute, Kashmir.
Vet Parasitol. 1989 Jan;30(3):253-8. doi: 10.1016/0304-4017(89)90020-4.
The osmotic fragility of erythrocytes in lambs experimentally infected with Dictyocaulus filaria was studied weekly for 71 weeks. In acute infection, the erythrocytic fragility increased from the third week of infection onwards, reached its peak by the eleventh week and declined thereafter. However, in the chronic immune-carrier stage, this increase in the fragility did not return to normal until the end of the experiment. This enhanced fragility showed a positive correlation with the faecal larval count, worm burden and the extent of lung damage in lambs.
对实验感染丝状网尾线虫的羔羊的红细胞渗透脆性进行了为期71周的每周研究。在急性感染中，红细胞脆性从感染后第三周开始增加，在第十一周达到峰值，此后下降。然而，在慢性免疫携带阶段，这种脆性增加直到实验结束才恢复正常。这种增强的脆性与羔羊的粪便幼虫计数、虫负荷和肺损伤程度呈正相关。
