肢端肥大症患者的脉络膜-视网膜厚度测量
Chorio-retinal thickness measurements in patients with acromegaly.
作者信息
Pekel G, Akin F, Ertürk M S, Acer S, Yagci R, Hıraali M C, Cetin E N
机构信息
Ophthalmology Department, Pamukkale University, Denizli, Turkey.
Endocrinology Department, Pamukkale University, Denizli, Turkey.
出版信息
Eye (Lond). 2014 Nov;28(11):1350-4. doi: 10.1038/eye.2014.216. Epub 2014 Sep 19.
PURPOSE
To compare choroidal, foveal, and peripapillary retinal thickness between patients with acromegaly and healthy adults.
METHODS
This prospective, cross-sectional, and comparative study included 30 patients with acromegaly (study group) and 30 healthy subjects (control group). The subfoveal choroidal thickness (SFCT), foveal thickness, and peripapillary retinal nerve fibre layer thickness were measured with spectral domain optical coherence tomography.
RESULTS
The mean SFCT in the study group and in the control eyes was 374.4±98.1 and 308.6±77.3 μm, respectively (P<0.001). The mean thinnest foveal thickness value was 233.2±22.4 μm in the acromegaly group and 222.8±13.9 μm in the control group (P=0.003). The mean peripapillary retinal nerve fibre layer thickness did not differ significantly between the groups (P=0.34).
CONCLUSION
The SFCT and foveal thickness were significantly higher in patients with acromegaly, whereas peripapillary retinal nerve fibre layer thickness was similar between the groups.
目的
比较肢端肥大症患者与健康成年人的脉络膜、黄斑中心凹及视乳头周围视网膜厚度。
方法
这项前瞻性、横断面比较研究纳入了30例肢端肥大症患者（研究组）和30名健康受试者（对照组）。采用光谱域光学相干断层扫描测量黄斑中心凹下脉络膜厚度（SFCT）、黄斑中心凹厚度及视乳头周围视网膜神经纤维层厚度。
结果
研究组和对照眼的平均SFCT分别为374.4±98.1μm和308.6±77.3μm（P<0.001）。肢端肥大症组最薄黄斑中心凹厚度的平均值为233.2±22.4μm，对照组为222.8±13.9μm（P=0.003）。两组间视乳头周围视网膜神经纤维层厚度的平均值无显著差异（P=0.34）。
结论
肢端肥大症患者的SFCT和黄斑中心凹厚度显著更高，而两组间视乳头周围视网膜神经纤维层厚度相似。
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