Hiruma Junichiro, Kano Rui, Kimura Utako, Takamori Kenji, Suga Yasushi, Hiruma Masataro, Hasegawa Atsuhiko, Tsuboi Ryoji
J Dermatol. 2014 Aug;41(8):743-5. doi: 10.1111/1346-8138.12575.
Trichophyton mentagrophytes were isolated from 19 of 20 guinea pigs in a children’s corner of a zoo. The nucleotide sequence identity of the internal transcribed spacer region among 19 guinea pig isolates was 99%, including the reference strain of animal type 3 of T. mentagrophytes. The genomic DNA of all isolates were investigated for the mating (MAT) gene by specific polymerase chain reaction. The alpha-box gene was detected in all 19 isolates, while the high-mobility-group (HMG) gene was detected in only one of 19 isolates. Therefore, the guinea pig population harbored at least 2 MAT types of Arthroderma vanbreuseghemii. The T. mentagrophytes that was prevalent in this population may constitute a constant source of infection for persons coming into contact with guinea pigs.
从动物园儿童区的20只豚鼠中的19只分离出须癣毛癣菌。19株豚鼠分离株内部转录间隔区的核苷酸序列同一性为99%，包括须癣毛癣菌动物型3的参考菌株。通过特异性聚合酶链反应对所有分离株的基因组DNA进行交配（MAT）基因检测。在所有19株分离株中均检测到α盒基因，而在19株分离株中仅1株检测到高迁移率族（HMG）基因。因此，豚鼠群体中至少存在2种范布列希米节皮菌的交配型。该群体中流行的须癣毛癣菌可能是接触豚鼠的人持续的感染源。
