Kim Jong Yeol, Noble Denis
Department of Medical Research, Korea Institute of Oriental Medicine, Yuseong-gu, Daejeon 305-811, Republic of Korea.
Department of Physiology, Anatomy & Genetics, University of Oxford, Parks Road, Oxford OX1 3PT, UK.
Prog Biophys Mol Biol. 2014 Sep;116(1):76-80. doi: 10.1016/j.pbiomolbio.2014.09.005. Epub 2014 Sep 18.
The history of the constitution perspective in medical care dates back thousands of years and extends from the East to the West. Among the various forms of constitutional medicine, Sasang constitutional medicine (SCM) is a holistic, tailored medical approach that is based on a well-structured theoretical system that includes physiopathological disciplines. Scientific evidence has demonstrated that SCM typology has a constitution-specific basis in anthropometrics, physiological characteristics, disease vulnerability, and genetic origins. Furthermore, the recent rise of systems biology, which requires whole body modeling, uses a state-of-the-art approach in interpreting the holistic spirit of Oriental medicine. This article aims to provide an overview of the recent achievements in SCM research and to discuss how the concept of balance in SCM may contribute to the development of large scale modeling in systems biology.
医学保健中体质观的历史可追溯到数千年前，且从东方延伸至西方。在各种形式的体质医学中，韩医学（SCM）是一种全面、个性化的医学方法，它基于一个结构完善的理论体系，其中包括生理病理学学科。科学证据表明，韩医学类型在人体测量学、生理特征、疾病易感性和遗传起源方面具有特定体质基础。此外，最近兴起的系统生物学需要对全身进行建模，它采用了一种先进的方法来诠释东方医学的整体精神。本文旨在概述韩医学研究的最新成果，并探讨韩医学中的平衡概念如何有助于系统生物学中大规模建模的发展。
