Talley J D, Jones E L, Weintraub W S, King S B
Division of Cardiology, Emory University School of Medicine, Atlanta, Georgia.
Circulation. 1989 Jun;79(6 Pt 2):I126-31.
This study was performed to determine the procedural characteristics and in-hospital complications associated with failed percutaneous transluminal coronary angioplasty that necessitates coronary artery bypass graft surgery. The study population consisted of 316 patients from 1980 to 1986; 202 patients (64%) had emergency coronary artery bypass graft surgery and the remainder elective surgery during the same hospitalization. Mean age of the population was 56 +/- 9 years, 69% were male, and 69% had single-vessel disease. The failed percutaneous transluminal coronary angioplasty occurred most commonly on the first vessel attempted and was usually secondary to coronary artery dissection. Analysis of surgical technique revealed increased use of intra-aortic balloon pump in the emergency group (24% vs. 2% in the elective group, p less than 0.05). Overall, 2.0 +/- 1.0 (mean +/- SD) bypass grafts were placed, with increased use of the internal thoracic artery in the elective (32%) versus the emergency group (20%, p less than 0.05). A new, nonfatal, postprocedural Q-wave myocardial infarction occurred in 18% and developed more frequently in the emergency (27%) than in the elective (4%) cohorts. There were six in-hospital deaths (1.9%), an incidence which did not differ between groups. This analysis revealed a significant difference in operative technique between the emergency and the elective coronary artery bypass graft patients. Preoperative ischemia was significantly related to the development of the Q-wave myocardial infarction, yet not to in-hospital mortality.(ABSTRACT TRUNCATED AT 250 WORDS)
本研究旨在确定与经皮腔内冠状动脉成形术失败相关的手术特征及院内并发症,这些失败病例需要进行冠状动脉旁路移植手术。研究对象为1980年至1986年的316例患者;其中202例(64%)在同一住院期间接受了急诊冠状动脉旁路移植手术,其余患者接受择期手术。研究人群的平均年龄为56±9岁,69%为男性,69%患有单支血管病变。经皮腔内冠状动脉成形术失败最常发生在首次尝试的血管,通常继发于冠状动脉夹层。手术技术分析显示,急诊组主动脉内球囊泵的使用增加(24% vs. 择期组的2%,p<0.05)。总体而言,共植入2.0±1.0(均值±标准差)条旁路移植血管,择期组(32%)与急诊组(20%,p<0.05)相比,胸廓内动脉的使用增加。18%的患者出现了新的、非致命的术后Q波心肌梗死,且在急诊组(27%)比择期组(4%)更常见。院内死亡6例(1.9%),两组发生率无差异。该分析显示急诊和择期冠状动脉旁路移植患者的手术技术存在显著差异。术前缺血与Q波心肌梗死的发生显著相关,但与院内死亡率无关。(摘要截短于250字)