更广泛自闭症表型的新访谈和观察测量方法：组间差异
New interview and observation measures of the broader autism phenotype: group differentiation.
作者信息
de Jonge Maretha, Parr Jeremy, Rutter Michael, Wallace Simon, Kemner Chantal, Bailey Anthony, van Engeland Herman, Pickles Andrew
机构信息
Department of Psychiatry, University Medical Center Utrecht, Room A01.468, Postbox 85500, 3508 GA, Utrecht, The Netherlands,
出版信息
J Autism Dev Disord. 2015 Apr;45(4):893-901. doi: 10.1007/s10803-014-2230-7.
To identify the broader autism phenotype (BAP), the Family History Interview subject and informant versions and an observational tool (Impression of Interviewee), were developed. This study investigated whether the instruments differentiated between parents of children with autism, and parents of children with Down syndrome (DS). The BAP scores of parents of 28 multiplex autism families were compared with parents from, 32 DS families. The BAP measures provided good group differentiation but when considered together, the subject interview did not improve group differentiation. The differentiation was better for fathers than mothers. The measures do carry an important degree of validity; whether they can differentiate the BAP from other social disorders should be tested.
为了识别广泛的自闭症表型（BAP），开发了家族史访谈的受试者版和知情者版以及一种观察工具（对受访者的印象）。本研究调查了这些工具能否区分自闭症儿童的父母和唐氏综合征（DS）儿童的父母。将28个多重自闭症家庭的父母的BAP得分与32个DS家庭的父母的得分进行了比较。BAP测量提供了良好的组间区分，但综合考虑时，受试者访谈并未改善组间区分。父亲的区分效果比母亲更好。这些测量确实具有重要程度的效度；它们能否将BAP与其他社会障碍区分开来有待检验。
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