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乳腺脓肿内的骨形成。

Bone formation within a breast abscess.

作者信息

Mannu Gurdeep Singh, Ahmed Farid, Cunnick Giles, Mungalsingh Naren

机构信息

Department of Breast Surgery, Buckinghamshire NHS Trust, UK.

Department of Pathology, Buckingamshire NHS Trust, UK.

出版信息

BMJ Case Rep. 2014 Sep 22;2014:bcr2013202384. doi: 10.1136/bcr-2013-202384.

DOI:10.1136/bcr-2013-202384
PMID:25246453
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4173640/
Abstract

We present a rare case of osseous metaplasia in a poorly healing breast abscess. An 87-year-old woman was referred to the breast surgery clinic with a painful lump in her right breast. Initial imaging and core biopsy suggested a breast abscess. Despite several courses of antibiotics and repeated attempts at aspiration the painful lesion persisted. It was eventually surgically excised in its entirety and final histopathology showed the presence of bone formation within the abscess. The patient's symptoms subsequently resolved. To the best of our knowledge, this is the first case in the literature, of osseous metaplasia within a breast abscess in the absence of malignancy.

摘要

我们报告了一例愈合不良的乳腺脓肿中发生骨化生的罕见病例。一名87岁女性因右乳出现疼痛性肿块被转诊至乳腺外科门诊。初步影像学检查和粗针活检提示为乳腺脓肿。尽管接受了几个疗程的抗生素治疗并多次尝试穿刺抽吸,但疼痛性病变仍持续存在。最终将其完整手术切除,最终组织病理学检查显示脓肿内有骨形成。患者的症状随后得到缓解。据我们所知,这是文献中首例在无恶性肿瘤情况下乳腺脓肿内发生骨化生的病例。

相似文献

1
Bone formation within a breast abscess.乳腺脓肿内的骨形成。
BMJ Case Rep. 2014 Sep 22;2014:bcr2013202384. doi: 10.1136/bcr-2013-202384.
2
Squamous metaplasia of lactiferous ducts (SMOLD): an under-recognised entity.乳腺导管的鳞状化生(SMOLD):一种认识不足的实体。
BMJ Case Rep. 2020 Dec 9;13(12):e237568. doi: 10.1136/bcr-2020-237568.
3
Rate of malignancies in breast abscesses and argument for ultrasound drainage.乳腺脓肿的恶性肿瘤发生率及超声引流的依据
Am J Surg. 2006 Dec;192(6):869-72. doi: 10.1016/j.amjsurg.2006.08.060.
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[Spontaneous cholecystocutaneous fistula presenting in the right breast].
Ugeskr Laeger. 2012 Apr 30;174(18):1235-6.
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Subareolar abscess of the breast: diagnosis by fine-needle aspiration.乳腺乳晕下脓肿:细针穿刺诊断法
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Breast abscess due to Finegoldia magna in a non-puerperal women.非产褥期女性因大芬戈尔德菌引起的乳房脓肿。
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Subareolar abscess associated with squamous metaplasia of lactiferous ducts.乳晕下脓肿伴输乳管鳞状化生
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Purulent discharge from the nipples: a quiz. Zuska's disease.乳头脓性分泌物:一则问答。祖斯卡病。
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Subareolar abscess in a male breast: cytological characterisation and distinction from other benign and malignant squamous cell aspirate.男性乳腺乳晕下脓肿:细胞学特征及与其他良性和恶性鳞状细胞抽吸物的鉴别
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Pilonidal abscess of the breast.
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引用本文的文献

1
Benign Osseous Metaplasia of the Breast: A Rare Breast Lesion-Case Report With Clinicopathologic Features and Review of the Literature.乳腺良性骨化生:一种罕见的乳腺病变——病例报告及临床病理特征分析并文献复习
Case Rep Pathol. 2025 Jun 19;2025:8854614. doi: 10.1155/crip/8854614. eCollection 2025.
2
Benign osseous metaplasia of the breast infiltrated by invasive pleomorphic lobular carcinoma: A case report.浸润性多形性小叶癌累及的乳腺良性骨化生:一例报告
Int J Surg Case Rep. 2022 Oct;99:107716. doi: 10.1016/j.ijscr.2022.107716. Epub 2022 Sep 30.
3
Osseous Metaplasia in Hemangiomas of the Breast: Case Reports and Literature Review.乳腺血管瘤中的骨化生:病例报告与文献综述
J Breast Cancer. 2021 Apr;24(2):229-234. doi: 10.4048/jbc.2021.24.e7. Epub 2021 Feb 8.

本文引用的文献

1
An unusual breast lump: osseous metaplasia.一例罕见的乳腺肿块:骨化生
BMJ Case Rep. 2013 Feb 4;2013:bcr2012008239. doi: 10.1136/bcr-2012-008239.
2
Extramedullary hemopoiesis in a thyroid nodule with extensive bone metaplasia and mature bone formation.甲状腺结节中存在髓外造血,并伴有广泛骨化生和成熟骨形成。
Thyroid. 2003 Sep;13(9):877-80. doi: 10.1089/105072503322401087.
3
Osseous metaplasia of the breast: diagnosis with stereotactic core biopsy.
Breast J. 2002 Jan-Feb;8(1):50-2. doi: 10.1046/j.1524-4741.2002.08011.x.
4
Primary osteogenic sarcoma of the breast.乳腺原发性骨肉瘤
Acta Cytol. 1982 Jul-Aug;26(4):512-6.
5
Extraosseous osteogenic sarcoma of the breast: mammographic and pathologic findings.
Radiology. 1984 Jan;150(1):34. doi: 10.1148/radiology.150.1.6580676.
6
Breast neoplasms containing bone and cartilage.含有骨和软骨的乳腺肿瘤。
Virchows Arch A Pathol Anat Histopathol. 1983;400(3):287-95. doi: 10.1007/BF00612190.
7
The occurrence of bone and cartilage in mammary tumors.乳腺肿瘤中骨和软骨的出现。
Am J Clin Pathol. 1969 May;51(5):610-8. doi: 10.1093/ajcp/51.5.610.