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含有骨和软骨的乳腺肿瘤。

Breast neoplasms containing bone and cartilage.

作者信息

Spagnolo D V, Shilkin K B

出版信息

Virchows Arch A Pathol Anat Histopathol. 1983;400(3):287-95. doi: 10.1007/BF00612190.

DOI:10.1007/BF00612190
PMID:6310857
Abstract

A total of 307 breast neoplasms and tumour-like conditions were reviewed to assess the frequency with which bone and/or cartilage occurred. Of 90 fibroadenomas, 1 (1.1%) and 2 of 158 breast carcinomas (1.3%) contained bone, one benign mesenchymoma contained cartilage, and one benign "mixed" tumour (pleomorphic adenoma) displayed cartilage and bone. Twenty-two papillomas and 34 cases of gynaecomastia did not contain any cartilage or bone. This study confirms the impression that the occurrence of bone or cartilage in human breast neoplasms is rare. These lesions are briefly discussed with reference to the pertinent literature.

摘要

共对307例乳腺肿瘤和肿瘤样病变进行了回顾,以评估骨和/或软骨出现的频率。在90例纤维腺瘤中,1例(1.1%)含有骨组织,在158例乳腺癌中有2例(1.3%)含有骨组织,1例良性间叶瘤含有软骨组织,1例良性“混合”瘤(多形性腺瘤)含有软骨和骨组织。22例乳头状瘤和34例男性乳腺增生症均未含有任何软骨或骨组织。本研究证实了人类乳腺肿瘤中骨或软骨的出现较为罕见这一观点。结合相关文献对这些病变进行了简要讨论。

相似文献

1
Breast neoplasms containing bone and cartilage.含有骨和软骨的乳腺肿瘤。
Virchows Arch A Pathol Anat Histopathol. 1983;400(3):287-95. doi: 10.1007/BF00612190.
2
The occurrence of bone and cartilage in mammary tumors.乳腺肿瘤中骨和软骨的出现。
Am J Clin Pathol. 1969 May;51(5):610-8. doi: 10.1093/ajcp/51.5.610.
3
[Mixed tumor of the breast (pleomorphic adenoma)].[乳腺混合瘤(多形性腺瘤)]
Ann Pathol. 1985;5(3):213-5.
4
Benign chondrolipomatous tumour of the breast.乳腺良性软骨脂肪瘤
Postgrad Med J. 1981 Feb;57(664):129-31. doi: 10.1136/pgmj.57.664.129.
5
Uterine tumors with mixed epithelial and mesenchymal elements.具有上皮和间充质混合成分的子宫肿瘤。
Semin Diagn Pathol. 1988 May;5(2):199-222.
6
Pleomorphic adenoma of the human breast. A report of a benign tumour closely mimicking a carcinoma clinically.人乳腺多形性腺瘤。一例临床上酷似癌的良性肿瘤报告。
Clin Oncol. 1982 Dec;8(4):361-5.
7
[Carcinoma arising within mammary fibroadenomas. A study of six patients].[乳腺纤维腺瘤内发生的癌。6例患者的研究]
Ann Pathol. 2000 Mar;20(2):110-4.
8
Breast carcinoma arising within fibroadenomas. Report of four observations.纤维腺瘤内发生的乳腺癌。四例报告。
Tunis Med. 2007 Oct;85(10):891-5.
9
Mixed mesenchymal differentiation in meningiomas.脑膜瘤中的混合间充质分化
J Pathol. 1975 Aug;116(4):253-8. doi: 10.1002/path.1711160408.
10
Chondrolipoangioma. A cartilage-containing benign mesenchymoma of soft tissue.软骨脂肪血管瘤。一种含有软骨的软组织良性间叶瘤。
Cancer. 1990 Dec 15;66(12):2636-41. doi: 10.1002/1097-0142(19901215)66:12<2636::aid-cncr2820661228>3.0.co;2-3.

引用本文的文献

1
Benign Osseous Metaplasia of the Breast: A Rare Breast Lesion-Case Report With Clinicopathologic Features and Review of the Literature.乳腺良性骨化生:一种罕见的乳腺病变——病例报告及临床病理特征分析并文献复习
Case Rep Pathol. 2025 Jun 19;2025:8854614. doi: 10.1155/crip/8854614. eCollection 2025.
2
Pleomorphic Adenoma of the Breast: A Rare Benign Lesion Masquerading as a Metaplastic Breast Carcinoma on Core-Needle Biopsy.乳腺多形性腺瘤:一种在粗针活检时伪装成化生性乳腺癌的罕见良性病变。
Cureus. 2023 May 10;15(5):e38827. doi: 10.7759/cureus.38827. eCollection 2023 May.
3
Benign osseous metaplasia of the breast infiltrated by invasive pleomorphic lobular carcinoma: A case report.

本文引用的文献

1
Mesenchymoma, the Mixed Tumor of Mesenchymal Derivatives.间叶瘤,间叶组织衍生物的混合性肿瘤。
Ann Surg. 1948 Feb;127(2):278-90. doi: 10.1097/00000658-194802000-00007.
2
Osteogenic sarcoma of the breast.乳腺骨肉瘤
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Salivary gland tumours and their mucins.唾液腺肿瘤及其黏蛋白。
浸润性多形性小叶癌累及的乳腺良性骨化生:一例报告
Int J Surg Case Rep. 2022 Oct;99:107716. doi: 10.1016/j.ijscr.2022.107716. Epub 2022 Sep 30.
4
Osseous Metaplasia in Hemangiomas of the Breast: Case Reports and Literature Review.乳腺血管瘤中的骨化生:病例报告与文献综述
J Breast Cancer. 2021 Apr;24(2):229-234. doi: 10.4048/jbc.2021.24.e7. Epub 2021 Feb 8.
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Metaplastic carcinomas of the breast without evidence of epithelial differentiation: a diagnostic approach for management.乳腺非上皮分化性间变性癌:一种诊断处理方法。
Histopathology. 2021 Apr;78(5):759-771. doi: 10.1111/his.14290. Epub 2020 Dec 16.
6
A Comparative Review of Mixed Mammary Tumors in Mammals.哺乳动物混合性乳腺肿瘤的比较研究
J Mammary Gland Biol Neoplasia. 2019 Jun;24(2):125-137. doi: 10.1007/s10911-018-9422-2. Epub 2018 Nov 28.
7
Benign osseous metaplasia of the breast: Case report.乳腺良性骨化生:病例报告
Int J Surg Case Rep. 2018;44:90-92. doi: 10.1016/j.ijscr.2018.02.025. Epub 2018 Feb 19.
8
Prognostic factors in metaplastic carcinoma of the breast: a multi-institutional study.乳腺化生性癌的预后因素:一项多机构研究。
Br J Cancer. 2015 Jan 20;112(2):283-9. doi: 10.1038/bjc.2014.592. Epub 2014 Nov 25.
9
Bone formation within a breast abscess.乳腺脓肿内的骨形成。
BMJ Case Rep. 2014 Sep 22;2014:bcr2013202384. doi: 10.1136/bcr-2013-202384.
10
Salivary gland-like tumours of the breast: surgical and molecular pathology.乳腺涎腺样肿瘤:外科手术与分子病理学
J Clin Pathol. 2003 Jul;56(7):497-506. doi: 10.1136/jcp.56.7.497.
J Pathol Bacteriol. 1959 Jan;77(1):131-40. doi: 10.1002/path.1700770114.
4
Mammary neoplasms of the bitch.母犬乳腺肿瘤
J Comp Pathol. 1958 Jan;68(1):1-22.
5
Sarcomas and related mesenchymal tumors of the breast.乳腺肉瘤及相关间叶组织肿瘤
Cancer. 1968 Jul;22(1):22-8. doi: 10.1002/1097-0142(196807)22:1<22::aid-cncr2820220105>3.0.co;2-r.
6
Cartilaginous metaplasia in a breast tumour.乳腺肿瘤中的软骨化生
J Pathol. 1969 Feb;97(2):385-7. doi: 10.1002/path.1710970227.
7
Carcinosarcoma of the breast.乳腺癌肉瘤
J Pathol. 1974 Feb;112(2):99-105. doi: 10.1002/path.1711120205.
8
Metaplastic breast carcinoma. Rare form of mammary cancer.化生性乳腺癌。一种罕见的乳腺癌类型。
N Y State J Med. 1973 May 1;73(9):1078-82.
9
A composite malignant tumour of the elderly female breast.老年女性乳房的复合性恶性肿瘤。
J Clin Pathol. 1970 Jul;23(5):414-22. doi: 10.1136/jcp.23.5.414.
10
The occurrence of bone and cartilage in mammary tumors.乳腺肿瘤中骨和软骨的出现。
Am J Clin Pathol. 1969 May;51(5):610-8. doi: 10.1093/ajcp/51.5.610.