Duhon Daniel J, Anton Canivan R, Ro Jae Y, Venta Luz A, Anton Rose C, Schwartz Mary R
Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, USA.
Department of Radiology, Houston Methodist Hospital, Houston, USA.
J Breast Cancer. 2021 Apr;24(2):229-234. doi: 10.4048/jbc.2021.24.e7. Epub 2021 Feb 8.
Unusual or prominent calcifications found on screening mammography may prompt additional radiologic and clinical work-up given the possible association with pre-malignant lesions, other high-risk lesions, or malignancies. Osseous metaplasia (OM) of the breast, also referred to as metaplastic ossification or heterotopic bone formation, is an uncommon finding that may present as radiographic calcification. There are isolated case reports of OM associated with benign or malignant tumors of the breast, as well as with a variety of non-neoplastic conditions. We report 2 cases of OM in the breast associated with a hemangioma and review the relevant literature. To the best of our knowledge, these are the first reported cases of this association in the breast.
在筛查乳腺钼靶检查中发现的异常或明显钙化，鉴于其可能与癌前病变、其他高危病变或恶性肿瘤相关，可能会促使进行额外的放射学和临床检查。乳腺骨化生（OM），也称为化生骨化或异位骨形成，是一种罕见的表现为放射学钙化的发现。有孤立的病例报告称OM与乳腺的良性或恶性肿瘤以及多种非肿瘤性疾病有关。我们报告2例乳腺OM与血管瘤相关的病例，并回顾相关文献。据我们所知，这是首次报道的乳腺中这种关联的病例。
