一例对S-1/顺铂联合曲妥珠单抗术前联合治疗有反应的胃癌病例
[A case of gastric cancer that responded to a preoperative combination therapy of S-1/CDDP plus trastuzumab].
作者信息
Sueoka Satoshi, Ito Akihiro, Kawanishi Jun, Sakakima Yoshikazu
机构信息
Dept. of Surgery, Toki General Hospital.
出版信息
Gan To Kagaku Ryoho. 2014 Sep;41(9):1155-7.
A 79-year-old man was diagnosed with advanced gastric cancer (cT3, N1, M0, cStage II B) showing regional bulky lymph node metastasis. Invasion of the pancreas and common hepatic artery was suspected. He was treated with S-1/CDDP plus trastuzumab therapy as a neoadjuvant chemotherapy (NAC) regimen. After two courses, significant tumor reduction was observed, and the patient underwent distal gastrectomy with D2 dissection. S-1/CDDP plus trastuzumab therapy as NAC for HER2-positive, advanced gastric cancer appears to be an effective treatment.
一名79岁男性被诊断为晚期胃癌（cT3、N1、M0，c期IIB），伴有区域淋巴结肿大转移。怀疑有胰腺和肝总动脉侵犯。他接受了S-1/顺铂联合曲妥珠单抗治疗作为新辅助化疗（NAC）方案。两个疗程后，观察到肿瘤明显缩小，患者接受了D2根治性远端胃切除术。S-1/顺铂联合曲妥珠单抗治疗作为HER2阳性晚期胃癌的新辅助化疗似乎是一种有效的治疗方法。
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