Mahmoud Hashemi Hamid, Mohammadi Farnoosh, Hasheminasab Mahboube, Mahmoud Hashemi Ali, Zahraei Shohreh, Mahmoud Hashemi Talieh
Full Professor, Department of Oral and Maxillofacial Surgery, Tehran University of Medical Sciences, Tehran, Iran.
Associate Professor, Department of Oral and Maxillofacial Surgery, Tehran University of Medical Sciences, Tehran, Iran.
J Oral Maxillofac Surg. 2015 Jan;73(1):18-21. doi: 10.1016/j.joms.2014.06.454. Epub 2014 Jul 5.
Povidone iodine is used primarily as an antiseptic to decrease surgical site infection. Its hemostatic and antiedematous properties in oral surgery also have been investigated recently.
A randomized controlled clinical trial was performed in 30 patients undergoing mandibular third molar removal in a split-mouth design. In the study group, a povidone iodine solution with a concentration of 0.5 mg/mL was used as the coolant and irrigant solution, whereas normal saline was used in the control group. Swelling (orotragus and mentotragus distances), trismus (maximum interincisal opening), and pain (visual analog scale score) were evaluated on postoperative days 2 and 7.
In the study group, a significant decrease in swelling and trismus was observed at the 2 postoperative visits (P = .00) compared with the control group. The decrease of pain in the study group was not statistically significant at either postoperative visit (P > .05). More patients (63%) were subjectively satisfied with the side treated with povidone iodine.
Povidone iodine irrigation is an inexpensive and safe method to lessen the postoperative sequelae of third molar surgery.
聚维酮碘主要用作防腐剂以减少手术部位感染。其在口腔外科手术中的止血和消肿特性最近也得到了研究。
采用随机对照临床试验，对30例接受下颌第三磨牙拔除术的患者采用双侧对照设计。研究组使用浓度为0.5mg/mL的聚维酮碘溶液作为冷却剂和冲洗液，而对照组使用生理盐水。在术后第2天和第7天评估肿胀情况（耳屏前和颏下距离）、张口受限（最大切牙间开口度）和疼痛情况（视觉模拟评分）。
与对照组相比，研究组在术后2次随访时肿胀和张口受限均显著减轻（P = .00）。研究组在术后任何一次随访时疼痛减轻均无统计学意义（P > .05）。更多患者（63%）主观上对聚维酮碘治疗侧感到满意。
聚维酮碘冲洗是一种廉价且安全的方法，可减轻第三磨牙手术后的后遗症。
