Yuce Esra, Dereci Omur, Altin Nazli, Koca Cansugul Efeoglu, Yazan Murude
Department of Oral and Maxillofacial Surgery, Istanbul Aydin University, Istanbul,Turkey.
Faculty of Dentistry, Department of Oral and Maxillofacial Surgery, Eskisehir Osmangazi University, Eskisehir, Turkey.
J Pak Med Assoc. 2020 Dec;70(12(B)):2304-2309. doi: 10.5455/JPMA.130.
To compare the clinical efficacy of different povidone iodine concentrations for the management of postoperative pain and swelling following mandibular third molar surgery.
The randomised, prospective, double-blind and controlled study was conducted from October 2016 to January 2018 at the Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Biruni University, Istanbul, Turkey, and comprised individuals aged 18-30 years who underwent surgical removal of pathology-free completely unerrupted mandibular lower third molars. The participants were randomly assigned to four groups: Group I had saline-only controls, Group II was given 0.5% concentration of povidone iodine, Group III had 1% concentration of povidone iodine, and Group IV had 3% concentration of povidone iodine. Facial swelling and trismus were assessed on the 2nd and 7th postoperative days. Data was analysed using SPSS 22.
Of the 80 patients, 34(42.5%) were males and 46 (57.5%) were females with an overall mean age of 24.6±3.68 years. Each group had 20 (25%) subjects. All three concentrations of povidone iodine provided significant reduction in postoperative trismus compared to the controls. Trismus was less in Group III and Group IV compared to Group II up to 7 days after surgery.
Irrigation with 3% povidone iodine concentration was found to be more effective in reducing the level of facial swelling after impacted third molar surgery. (Clinical Trials.gov Identifier: NCT03894722).
比较不同浓度聚维酮碘在下颌第三磨牙手术后疼痛和肿胀管理中的临床疗效。
这项随机、前瞻性、双盲对照研究于2016年10月至2018年1月在土耳其伊斯坦布尔比鲁尼大学牙科学院口腔颌面外科进行，纳入年龄在18 - 30岁、接受手术拔除无病变完全未萌出下颌第三磨牙的个体。参与者被随机分为四组：第一组仅用生理盐水作为对照，第二组给予0.5%浓度的聚维酮碘，第三组给予1%浓度的聚维酮碘，第四组给予3%浓度的聚维酮碘。在术后第2天和第7天评估面部肿胀和张口受限情况。使用SPSS 22分析数据。
80例患者中，男性34例（42.5%），女性46例（57.5%），总体平均年龄为24.6±3.68岁。每组有20例（25%）受试者。与对照组相比，所有三种浓度的聚维酮碘均能显著减轻术后张口受限。术后7天内，第三组和第四组的张口受限程度低于第二组。
发现用3%浓度的聚维酮碘冲洗在减少阻生第三磨牙手术后的面部肿胀程度方面更有效。（临床试验注册号：NCT03894722）
