Magnesium monoperoxophtalate: an efficient single oxygen atom donor in DNA cleavage catalyzed by metalloporphyrin.
作者信息
Pratviel G, Bernadou J, Ricci M, Meunier B
机构信息
Laboratoire de Chimie de Coordination du CNRS, Toulouse, France.
出版信息
Biochem Biophys Res Commun. 1989 May 15;160(3):1212-8. doi: 10.1016/s0006-291x(89)80132-9.
PMID:2525035
Abstract
The peracid compound magnesium monoperoxophtalate (MMPP), water-soluble at physiological pH, behaves as a promising oxygen donor in the oxidative cleavage of DNA catalyzed by meso-tetrakis-(4-N-methylpyridyl)porphyrinatomanganese(III) pentaacetate. Shown on cleavage of supercoiled phi X174 DNA, MMPP is significantly more efficient than KHSO5, another recently developed single oxygen atom donor (Fouquet et al., J. Chem. Soc., Chem. Commun., 1987, 1169).
摘要
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