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门诊患者神经肌肉阻滞的管理。

Management of neuromuscular blockade in ambulatory patients.

作者信息

Schreiber Jan-Uwe

机构信息

Department of Anesthesia, Maastricht University Medical Center, Maastricht, The Netherlands.

出版信息

Curr Opin Anaesthesiol. 2014 Dec;27(6):583-8. doi: 10.1097/ACO.0000000000000134.

Abstract

PURPOSE OF REVIEW

The use of neuromuscular blocking agents in ambulatory surgery has been described as a double-edged sword. Muscle relaxants may improve the outcome following endotracheal intubation and could be helpful for the surgeon to some extent. However, these agents might increase the risk of postoperative complications because of residual paralysis. This review should summarize recent developments in neuromuscular blockade, neuromuscular monitoring, and reversal with a special reference to day case surgery.

RECENT FINDINGS

The use of neuromuscular blocking agents begs a risk of postoperative muscle weakness and has been associated with adverse respiratory events. From the surgical side, there could be an increased request for a more intense neuromuscular block during laparoscopic surgery. Therefore, the use of quantitative neuromuscular monitoring and selective reversal binding agents may gain more importance in the future. For the reversal of a shallow neuromuscular block, cholinesterase inhibitors are still appropriate.

SUMMARY

The management of neuromuscular blocks in day case surgery requests a comprehensive approach that should include an adequate dosing of the muscle relaxant, quantitative objective monitoring, and a sufficient and appropriate reversal.

摘要

综述目的

在门诊手术中使用神经肌肉阻滞剂可谓一把双刃剑。肌肉松弛剂可能会改善气管插管后的结果,并且在一定程度上对外科医生有所帮助。然而,由于残余麻痹,这些药物可能会增加术后并发症的风险。本综述旨在总结神经肌肉阻滞、神经肌肉监测及逆转方面的最新进展,并特别提及日间手术。

最新发现

使用神经肌肉阻滞剂存在术后肌肉无力的风险,并与不良呼吸事件相关。从外科角度来看,在腹腔镜手术期间可能会更频繁地要求更深度的神经肌肉阻滞。因此,未来使用定量神经肌肉监测和选择性逆转结合剂可能会变得更加重要。对于浅度神经肌肉阻滞的逆转,胆碱酯酶抑制剂仍然适用。

总结

日间手术中神经肌肉阻滞的管理需要综合方法,包括肌肉松弛剂的适当给药、定量客观监测以及充分且合适的逆转。

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