Babanejad Mehran, Najafi Farid, Hashemian Amir Hossein, Parizad Eskandar Gholami, Delpisheh Ali, Asadollahi Khairollah
J Pak Med Assoc. 2014 Aug;64(8):936-40.
To investigate the association between lifestyle risk factors and impaired fasting glucose level.
The large-scale, community-based, cross-sectional study was conducted in 2012 in Ilam province, Iran, and comprised 150 impaired fasting glucose cases and 450 controls. Face-to-face interviews were conducted using a standard lifestyle questionnaire, and subjects were checked for fasting plasma glucose. Chi-square test and multivariate logistic regression were used for statistical analysis.
Of the 600 participants, 172 (28.7%) were males and 428 (71.3%) were females. Their ages ranged from 20 to 83 years with a mean of 48.9 +/- 14.2 years for the cases and 45.5 +/- 13.4 years for the controls (p < 0.008). There was no statistically significant difference in terms of age, gender, marital status, location, family history of diabetes and body mass index in the two groups (p > 0.05). Using multivariate logistic regression, ghee consumption increased the risk of impaired fasting glucose up to 2.2 folds (Odds Ratio = 1.28, 95% Confidence Interval: 0.75-2.2); inactivity up to 2.33 folds (Odds Ratio = 1.33, 95% Confidence Interval: 0.75-2.33) and smoking up to 3.13 folds (Odds Ratio = 1.46, 95% Confidence Interval: 0.68-3.13). The differences were not statistically significant.
Risk of impaired fasting glucose increases with lifestyle risk factors that need to be considered seriously by policy makers.
探讨生活方式风险因素与空腹血糖受损水平之间的关联。
2012年在伊朗伊拉姆省开展了一项大规模、基于社区的横断面研究，纳入150例空腹血糖受损病例和450例对照。使用标准生活方式问卷进行面对面访谈，并对受试者进行空腹血糖检测。采用卡方检验和多因素逻辑回归进行统计分析。
600名参与者中，172名（28.7%）为男性，428名（71.3%）为女性。他们的年龄在20至83岁之间，病例组平均年龄为48.9±14.2岁，对照组平均年龄为45.5±13.4岁（p<0.008）。两组在年龄、性别、婚姻状况、居住地、糖尿病家族史和体重指数方面无统计学显著差异（p>0.05）。采用多因素逻辑回归分析，食用酥油使空腹血糖受损风险增加至2.2倍（比值比=1.28，95%置信区间：0.75-2.2）；缺乏运动使风险增加至2.33倍（比值比=1.33，95%置信区间：0.75-2.33）；吸烟使风险增加至3.13倍（比值比=1.46，95%置信区间：0.68-3.13）。这些差异无统计学显著性。
空腹血糖受损风险随生活方式风险因素增加，政策制定者需认真考虑这些因素。
