Sargant N, Erlewyn-Lajeunesse M, Benger J
Children's Emergency Department, Bristol Royal Hospital for Children, University Hospitals Bristol, Bristol, UK.
Children's Allergy Clinic, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
Emerg Med J. 2015 Jan;32(1):83-4. doi: 10.1136/emermed-2014-203603. Epub 2014 Sep 24.
Anaphylaxis in children presents most frequently with respiratory features, and concern exists about the potential for diagnostic confusion with acute asthma. 84 cases of asthma requiring intensive care were identified. 11 cases met exclusion criteria, which left 73 cases for analysis using established anaphylaxis diagnostic criteria. 13/73 children (17.8%) were found to have sufficient clinical features for a diagnosis of anaphylaxis to be entertained, with 3/73 cases (4.1%) considered highly likely to be anaphylaxis. This study highlights the potential for diagnostic confusion and demonstrates the need to consider anaphylaxis in all children presenting with severe asthma.
儿童过敏反应最常表现为呼吸道症状，人们担心它可能与急性哮喘在诊断上产生混淆。研究确定了84例需要重症监护的哮喘病例。11例符合排除标准，剩余73例使用既定的过敏反应诊断标准进行分析。73名儿童中有13名（17.8%）被发现具有足以让人考虑诊断为过敏反应的临床特征，其中73例中有3例（4.1%）被认为极有可能是过敏反应。这项研究突出了诊断混淆的可能性，并表明对于所有出现严重哮喘的儿童都有必要考虑过敏反应。
