Bunkute Egle, Cummins Christopher, Crofts Fraser J, Bunce Gareth, Nabney Ian T, Flower Darren R
School of Life and Health Sciences and School of Engineering and Applied Science, University of Aston, Aston Triangle, Birmingham B4 7ET, UK.
Bioinformatics. 2015 Jan 15;31(2):295-6. doi: 10.1093/bioinformatics/btu637. Epub 2014 Sep 23.
A protein's isoelectric point or pI corresponds to the solution pH at which its net surface charge is zero. Since the early days of solution biochemistry, the pI has been recorded and reported, and thus literature reports of pI abound. The Protein Isoelectric Point database (PIP-DB) has collected and collated these data to provide an increasingly comprehensive database for comparison and benchmarking purposes. A web application has been developed to warehouse this database and provide public access to this unique resource. PIP-DB is a web-enabled SQL database with an HTML GUI front-end. PIP-DB is fully searchable across a range of properties.
The PIP-DB database and documentation are available at http://www.pip-db.org.
蛋白质的等电点或pI对应于其净表面电荷为零时的溶液pH值。自溶液生物化学早期以来，pI就已被记录和报道，因此关于pI的文献报道比比皆是。蛋白质等电点数据库（PIP-DB）收集并整理了这些数据，以提供一个日益全面的数据库用于比较和基准测试。已开发了一个网络应用程序来存储此数据库并向公众提供对这一独特资源的访问。PIP-DB是一个具有HTML GUI前端的支持网络的SQL数据库。PIP-DB可通过一系列属性进行全面搜索。
PIP-DB数据库及文档可在http://www.pip-db.org获取。
