Lee Soon Il, Heo Nae-Yun, Park Seung Ha, Joo Young-Don, Kim Il Hwan, Park Jeong-Ik, Kim Ji Yeon, Kim Seung Ho, Shim Hye Kyung
Departments of Internal Medicine, Inje University Haeundae Paik Hospital, Inje University College of Medicine, Busan, Korea.
Departments of Surgery, Inje University Haeundae Paik Hospital, Inje University College of Medicine, Busan, Korea.
Korean J Gastroenterol. 2014 Sep 25;64(3):168-72. doi: 10.4166/kjg.2014.64.3.168.
Hepatitis C virus (HCV) is one of the main viral causes of hepatocellular carcinoma (HCC) and is associated with lymphoproliferative disorder such as non-Hodgkin's lymphoma (NHL). However, there are only few case reports on concomitantly induced NHL and HCC by HCV. Herein, we report a case of synchronous NHL and HCC in a patient with chronic hepatitis C which was unexpectedly diagnosed during liver transplantation surgery. This case suggests that although intrahepatic lymph node enlargements are often considered as reactive or metastatic lymphadenopathy in chronic hepatitis C patients with HCC, NHL should also be considered as a differential diagnosis.
丙型肝炎病毒（HCV）是肝细胞癌（HCC）的主要病毒病因之一，且与淋巴增殖性疾病如非霍奇金淋巴瘤（NHL）相关。然而，关于HCV同时诱发NHL和HCC的病例报告仅有少数。在此，我们报告1例慢性丙型肝炎患者同时发生NHL和HCC的病例，该病例在肝移植手术期间意外被诊断出来。该病例表明，尽管在患有HCC的慢性丙型肝炎患者中，肝内淋巴结肿大常被视为反应性或转移性淋巴结病，但NHL也应被视为一种鉴别诊断。
