一例艰难梭菌感染并发急性呼吸窘迫综合征经粪便微生物群移植治疗的病例。
A case of Clostridium difficile infection complicated by acute respiratory distress syndrome treated with fecal microbiota transplantation.
作者信息
Kim Ji Eun, Gweon Tae-Geun, Yeo Chang Dong, Cho Young-Seok, Kim Gi Jun, Kim Jae Young, Kim Jong Wook, Kim Hyunho, Lee Hye Won, Lim Taeseok, Ham Hyoju, Oh Hyun Jin, Lee Yeongbok, Byeon Jaeho, Park Sung Soo
机构信息
Ji Eun Kim, Gi Jun Kim, Jae Young Kim, Jong Wook Kim, Hyunho Kim, Hye Won Lee, Taeseok Lim, Hyoju Ham, Hyun Jin Oh, Yeongbok Lee, Jaeho Byeon, Sung Soo Park, Department of Internal Medicine, Seoul St Mary's hospital, The Catholic University of Korea, College of Medicine, Seoul 137-701, South Korea.
出版信息
World J Gastroenterol. 2014 Sep 21;20(35):12687-90. doi: 10.3748/wjg.v20.i35.12687.
Acute respiratory distress syndrome is a life-threatening disorder caused mainly by pneumonia. Clostridium difficile infection (CDI) is a common nosocomial diarrheal disease. Disruption of normal intestinal flora by antibiotics is the main risk factor for CDI. The use of broad-spectrum antibiotics for serious medical conditions can make it difficult to treat CDI complicated by acute respiratory distress syndrome. Fecal microbiota transplantation is a highly effective treatment in patients with refractory CDI. Here we report on a patient with refractory CDI and acute respiratory distress syndrome caused by pneumonia who was treated with fecal microbiota transplantation.
急性呼吸窘迫综合征是一种主要由肺炎引起的危及生命的疾病。艰难梭菌感染（CDI）是一种常见的医院获得性腹泻病。抗生素破坏正常肠道菌群是CDI的主要危险因素。在治疗严重疾病时使用广谱抗生素会使治疗合并急性呼吸窘迫综合征的CDI变得困难。粪便微生物群移植是治疗难治性CDI患者的一种高效疗法。在此，我们报告一例因肺炎导致难治性CDI和急性呼吸窘迫综合征的患者接受粪便微生物群移植治疗的病例。
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