Nakanishi Rine, Budoff Matthew J
Los Angeles Biomedical Research Institute at Harbor-UCLA, Torrance, CA 90502, USA.
Scientifica (Cairo). 2014;2014:278039. doi: 10.1155/2014/278039. Epub 2014 Sep 1.
For a decade, coronary computed tomographic angiography (CCTA) has been used as a promising noninvasive modality for the assessment of coronary artery disease (CAD) as well as cardiovascular risks. CCTA can provide more information incorporating the presence, extent, and severity of CAD; coronary plaque burden; and characteristics that highly correlate with those on invasive coronary angiography. Moreover, recent techniques of CCTA allow assessing hemodynamic significance of CAD. CCTA may be potentially used as a substitute for other invasive or noninvasive modalities. This review summarizes risk stratification by anatomical and hemodynamic information of CAD, coronary plaque characteristics, and burden observed on CCTA.
十年来，冠状动脉计算机断层扫描血管造影（CCTA）一直被用作一种有前景的非侵入性方法，用于评估冠状动脉疾病（CAD）以及心血管风险。CCTA可以提供更多信息，包括CAD的存在、范围和严重程度；冠状动脉斑块负荷；以及与侵入性冠状动脉造影高度相关的特征。此外，CCTA的最新技术能够评估CAD的血流动力学意义。CCTA可能潜在地用作其他侵入性或非侵入性方法的替代方法。本综述总结了基于CCTA观察到的CAD的解剖和血流动力学信息、冠状动脉斑块特征及负荷进行的风险分层。
