Ormeci Necati
Department of Gastroenterology, Ankara University Faculty of Medicine, Ankara, Turkey.
Turk J Gastroenterol. 2014 Aug;25(4):358-64. doi: 10.5152/tjg.2014.13018.
Hydatid disease is caused by the larval stages of Echinococcus Granulosus. Most patients with hydatid disease have no symptoms, unless there is compression of vital organs such as the hepatic veins, portal vein, hepatic artery in the liver, bronchia in the lungs or the brain, resulting in life threatening complications like anaphylactic shock and sudden death. There are four treatment strategies for cystic echinococcosis (CE)- surgery, percutaneous methods, medical treatments and watch and wait strategies. Medical treatment with albendazol, mebendazole or prazyquentel may cure only 2/3 of patients with CE. More than 30% of patients will reoccur after stopping the treatment. Watch and wait strategy is followed for asymptomatic and small cysts or CE type IV and Type V cysts. Surgical treatments were the gold standard for treatment of CE until the last 30 years. Consequently, surgical methods decreased while percutaneous methods of treatment increased. Due to higher mortality, morbidity, recurrence rates, longer hospital stays and higher costs in comparison to percutaneous methods like PAIR and ÖRMECİ technique, surgical treatment must be limited for the complicated hydatid cyst. Both the PAIR and Örmeci techniques are safe and effective. However, the Örmeci technique offers a simpler, inexpensive method of treatment, with no mortality, lower morbidity, low recurrence rate, while being out patient based. It can be used as the first choice of treatment modality in patients with cysts type CE type one, CE type two, CE Type 3A and CE Type 3B. In this review, treatment modalities for CE, but mainly percutaneous treatment, will be discussed.
包虫病是由细粒棘球绦虫的幼虫阶段引起的。大多数包虫病患者没有症状,除非重要器官如肝脏中的肝静脉、门静脉、肝动脉,肺中的支气管或大脑受到压迫,从而导致危及生命的并发症,如过敏性休克和猝死。囊性棘球蚴病(CE)有四种治疗策略——手术、经皮治疗、药物治疗和观察等待策略。使用阿苯达唑、甲苯达唑或吡喹酮进行药物治疗可能仅能治愈2/3的CE患者。超过30%的患者在停药后会复发。对于无症状的小囊肿或CE-IV型和V型囊肿,采用观察等待策略。直到过去30年,手术治疗一直是CE治疗的金标准。因此,手术方法减少,而经皮治疗方法增加。与PAIR和ÖRMECİ技术等经皮治疗方法相比,手术治疗由于死亡率更高、发病率更高、复发率更高、住院时间更长且成本更高,对于复杂的包虫囊肿,手术治疗必须受到限制。PAIR和Örmeci技术都安全有效。然而,Örmeci技术提供了一种更简单、便宜的治疗方法,无死亡率、发病率较低、复发率低,且为门诊治疗。它可作为CE-1型、CE-2型、CE-3A和CE-3B型囊肿患者的首选治疗方式。在本综述中,将讨论CE的治疗方式,主要是经皮治疗。