Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, College of Medicine, Ohio State University, Columbus, Ohio.
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, College of Medicine, Ohio State University, Columbus, Ohio.
Fertil Steril. 2014 Nov;102(5):1416-21. doi: 10.1016/j.fertnstert.2014.07.1247. Epub 2014 Sep 23.
To examine the association between infertility treatment and subsequent symptoms of postpartum depression.
Cross-sectional study.
Not applicable.
PATIENT(S): Women who delivered live-born infants from 2009-2010.
INTERVENTION(S): None.
MAIN OUTCOME MEASURE(S): Odds of symptoms of postpartum depression.
RESULT(S): Data were obtained from the Center for Disease Control and Prevention's Pregnancy Risk Assessment Monitoring System (PRAMS). Data on infertility treatment were available for 16 states in which mothers were sampled 2 to 4 months after delivery to complete the standardized PRAMS questionnaire. Infertility treatment status was as reported on the birth certificate. Maternal mental health was obtained via the maternal questionnaire. Data were analyzed in Stata 12.0 with sample weights to produce population-based estimates. Among the 42,614 women who resided in states in which infertility treatment data were collected, infertility treatment status was missing for 2,277 (5.3%) women. Among the 40,337 eligible women, 12.9% reported feeling down, depressed or sad, and 6.0% reported feeling hopeless. These women were considered to have symptoms of postpartum depression. Even after adjustment for confounders, there was no independent association between infertility treatment status and symptoms of postpartum depression. In contrast, having a child admitted to neonatal intensive care, smoking, experiencing a higher number of stressors in the 12 months before delivery, and a history of having prepregnancy mental health care were associated with an increased odds of having symptoms of postpartum depression.
CONCLUSION(S): In a population-based sample of U.S. women, conceiving with the help of infertility treatment did not increase the odds of experiencing symptoms of postpartum depression.
研究不孕治疗与产后抑郁症状之间的关系。
横断面研究。
不适用。
2009-2010 年间分娩活产儿的女性。
无。
产后抑郁症状的几率。
数据来自疾病控制和预防中心的妊娠风险评估监测系统（PRAMS）。在对产后 2-4 个月完成标准化 PRAMS 问卷的母亲进行抽样的 16 个州中，获得了关于不孕治疗的数据。不孕治疗状况根据出生证明报告。产妇心理健康通过产妇问卷获得。在 Stata 12.0 中进行数据分析，使用样本权重得出基于人群的估计值。在居住在收集不孕治疗数据的州的 42614 名妇女中，有 2277 名（5.3%）妇女的不孕治疗状况缺失。在 40337 名合格妇女中，12.9%报告感到沮丧、抑郁或悲伤，6.0%报告感到绝望。这些妇女被认为患有产后抑郁症状。即使在调整混杂因素后，不孕治疗状况与产后抑郁症状之间也没有独立的关联。相比之下，孩子被送入新生儿重症监护病房、吸烟、在分娩前 12 个月经历更多的压力源以及有孕前心理健康护理史，与产后抑郁症状的几率增加有关。
在一项基于人群的美国妇女样本中，借助不孕治疗怀孕并不会增加产后抑郁症状的几率。
