Hwang Su-In, Yoon Young-Jin, Sung Soo-Hyun, Cho Su-Jin, Park Jang-Kyung
Department of Korean Medicine, School of Korean Medicine, Pusan National University, Yangsan 50612, Republic of Korea.
Department of Korean Medicine Obstetrics and Gynecology, School of Korean Medicine, Pusan National University, Yangsan 50612, Republic of Korea.
Healthcare (Basel). 2023 Oct 10;11(20):2704. doi: 10.3390/healthcare11202704.
This systematic review and meta-analysis aimed to evaluate the efficacy and safety of acupuncture in treating emotional problems in women with infertility. We searched for randomized controlled trials using acupuncture treatment for emotional problems in women with infertility using 11 databases from their inception to 30 June 2023. The control intervention included no treatment, sham acupuncture treatment, and conventional treatment. The primary outcome was emotion-related rating scales, and the secondary outcomes were total effectiveness rate, quality of life, clinical pregnancy rate, and adverse events. Twelve randomized controlled trials involving 1930 participants were included. A meta-analysis of these studies indicated that, as compared to the control treatment, acupuncture significantly improved the State-Trait Anxiety Inventory, Self-rating Anxiety Scale, Amsterdam Preoperative Anxiety and Information Scale, and Self-rating Depression Scale scores, which were the primary emotion-related outcomes. Furthermore, the meta-analysis demonstrated that acupuncture treatment had a significant effect on the clinical pregnancy rate, which was the secondary outcome. No adverse events were reported in any of the studies. Our findings demonstrate the potential of acupuncture for treating emotional problems in women with infertility. However, well-designed and high-quality randomized clinical trials are required to confirm the effectiveness and safety of acupuncture treatment. The protocol of the current study was registered in PROSPERO (registration number: CRD42020166119).
本系统评价和荟萃分析旨在评估针刺治疗不孕症女性情绪问题的疗效和安全性。我们使用11个数据库，检索了从数据库建立至2023年6月30日期间针刺治疗不孕症女性情绪问题的随机对照试验。对照干预措施包括不治疗、假针刺治疗和传统治疗。主要结局为与情绪相关的评定量表，次要结局为总有效率、生活质量、临床妊娠率和不良事件。纳入了12项涉及1930名参与者的随机对照试验。对这些研究的荟萃分析表明，与对照治疗相比，针刺显著改善了状态-特质焦虑量表、自评焦虑量表、阿姆斯特丹术前焦虑和信息量表以及自评抑郁量表的评分，这些是主要的与情绪相关的结局。此外，荟萃分析表明针刺治疗对作为次要结局的临床妊娠率有显著影响。在任何研究中均未报告不良事件。我们的研究结果表明针刺治疗不孕症女性情绪问题具有潜力。然而，需要设计良好且高质量的随机临床试验来证实针刺治疗的有效性和安全性。本研究方案已在国际前瞻性系统评价注册库（PROSPERO）注册（注册号：CRD42020166119）。
