Kutilin D S, Bondarenko T I, Kornienko I V, Mikhaleva I I
South Federal University, Rostov-on-Don, Russia.
Bull Exp Biol Med. 2014 Sep;157(5):616-9. doi: 10.1007/s10517-014-2628-4. Epub 2014 Sep 26.
Subcutaneous injections of exogenous delta sleep-inducing peptide in a dose of 100 μg/kg (monthly, 5-day courses) to rats of various age groups (2-24 months) were followed by an increase in the expression of genes for SOD 1 (Sod1) and glutathione peroxidase 1 (Gpx1) in the brain and nucleated blood cells. The expression of these genes was shown to decrease during physiological aging of the body.
对不同年龄组(2至24个月)的大鼠皮下注射剂量为100μg/kg的外源性δ睡眠诱导肽(每月,为期5天的疗程)后,大脑和有核血细胞中SOD 1(Sod1)和谷胱甘肽过氧化物酶1(Gpx1)的基因表达增加。这些基因的表达在身体生理衰老过程中会下降。