Samarawickrema N A, Tabrizi S N, Young E, Gunawardena P, Garland S M
Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC, Australia
Department of Microbiology and Infectious Diseases, The Royal Women's Hospital, Parkville, VIC, Australia Department of Obstetrics and Gynaecology, University of Melbourne, Parkville, VIC, Australia Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, VIC, Australia.
Int J STD AIDS. 2015 Sep;26(10):733-9. doi: 10.1177/0956462414552813. Epub 2014 Sep 25.
The prevalences of Trichomonas vaginalis, Chlamydia trachomatis, Neisseria gonorrhoeae, and human papillomavirus (HPV) in Sri Lanka are not well reported; the objective of this study is to describe the prevalences of these four sexually transmitted infections among attendees of sexual health clinic in an urban setting. Vaginal swabs were collected from consenting women attending a sexual health clinic and tested for the presence of the above sexually transmitted infections using nucleic acid amplification techniques. Basic demographic details were sought from each participant (483 women of age range 14-61, median 30 years, IQR 12 years) via a research assistant-administered questionnaire. Overall, a prevalence of T. vaginalis, C. trachomatis, N. gonorrhoeae and HPV was 2.3%, (95% CI: 1.2-4.1%), 8.2% (95% CI: 5.6-11.4%), 7.6% (95% CI: 5.2-10.8%), and 44.4% (95% CI: 39.8-49.1%), respectively. Among the 197 positive for HPV, HPV6 accounted for 23.1%, HPV16 (12.5%), then HPV11, HPV66 and HPV58 were the commonest. Vaccine-related types (6/11/16/18) were detected in 59.9% of cases (95%CI: 52.7-66.8%). The high prevalence of sexually transmitted infections (45.2%) is a potential risk factor for an increase in HIV infections in the country and the high carriage of HPV supports the need for cervical cancer screening and prevention programmes.
斯里兰卡阴道毛滴虫、沙眼衣原体、淋病奈瑟菌和人乳头瘤病毒（HPV）的流行情况鲜有报道；本研究的目的是描述城市地区性健康诊所就诊者中这四种性传播感染的流行情况。从同意参与的性健康诊所就诊女性中采集阴道拭子，采用核酸扩增技术检测上述性传播感染的存在情况。通过研究助理管理的问卷，收集了每位参与者（483名年龄在14 - 61岁之间、中位数30岁、四分位距12岁的女性）的基本人口统计学细节。总体而言，阴道毛滴虫、沙眼衣原体、淋病奈瑟菌和HPV的流行率分别为2.3%（95%置信区间：1.2 - 4.1%）、8.2%（95%置信区间：5.6 - 11.4%）、7.6%（95%置信区间：5.2 - 10.8%）和44.4%（95%置信区间：39.8 - 49.1%）。在197例HPV阳性者中，HPV6占23.1% ，HPV16占（12.5%），其次HPV11、HPV66和HPV58最为常见。59.9%的病例（95%置信区间：52.7 - 66.8%）检测到与疫苗相关的型别（6/11/16/18）。性传播感染的高流行率（45.2%）是该国HIV感染增加的潜在危险因素，HPV的高携带率支持了宫颈癌筛查和预防计划的必要性。
