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Letter by Molkentin regarding article, "The absence of evidence is not evidence of absence: the pitfalls of Cre Knock-Ins in the c-Kit Locus".

作者信息

Molkentin Jeffery D

机构信息

Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Howard Hughes Medical Institute, OH.

出版信息

Circ Res. 2014 Sep 26;115(8):e21-3. doi: 10.1161/CIRCRESAHA.114.305011.

DOI:10.1161/CIRCRESAHA.114.305011
PMID:25258403
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4278750/
Abstract
摘要

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1
Letter by Molkentin regarding article, "The absence of evidence is not evidence of absence: the pitfalls of Cre Knock-Ins in the c-Kit Locus".莫尔肯廷就文章《缺乏证据并非没有证据:c-Kit基因座中Cre基因敲入的陷阱》所写的信件。
Circ Res. 2014 Sep 26;115(8):e21-3. doi: 10.1161/CIRCRESAHA.114.305011.
2
Absence of evidence is not evidence of absence: pitfalls of cre knock-ins in the c-Kit locus.缺乏证据并非没有证据:c-Kit基因座中cre敲入的陷阱。
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3
Response to Molkentin's letter to the editor regarding article, "the absence of evidence is not evidence of absence: the pitfalls of Cre knock-ins in the c-kit locus".对莫尔肯廷致编辑的信的回应,该信涉及文章《缺乏证据并非没有证据:c-kit基因座中Cre敲入的陷阱》
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4
c-kit+ cells minimally contribute cardiomyocytes to the heart.c-kit+ 细胞对心脏的心肌细胞生成贡献极小。
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本文引用的文献

1
Absence of evidence is not evidence of absence: pitfalls of cre knock-ins in the c-Kit locus.缺乏证据并非没有证据:c-Kit基因座中cre敲入的陷阱。
Circ Res. 2014 Aug 1;115(4):415-8. doi: 10.1161/CIRCRESAHA.114.304676. Epub 2014 Jun 25.
2
c-kit+ cells minimally contribute cardiomyocytes to the heart.c-kit+ 细胞对心脏的心肌细胞生成贡献极小。
Nature. 2014 May 15;509(7500):337-41. doi: 10.1038/nature13309. Epub 2014 May 7.
3
Response to Torella et al.对托雷拉等人的回应
Circ Res. 2014 Feb 14;114(4):e27. doi: 10.1161/CIRCRESAHA.114.303361.
4
CreER(T2) expression from within the c-Kit gene locus allows efficient inducible gene targeting in and ablation of mast cells.CreER(T2) 在 c-Kit 基因座内的表达允许在肥大细胞中进行有效的诱导性基因靶向和消融。
Eur J Immunol. 2014 Jan;44(1):296-306. doi: 10.1002/eji.201343731. Epub 2013 Oct 14.
5
Are resident c-Kit+ cardiac stem cells really all that are needed to mend a broken heart?驻留的c-Kit+心脏干细胞真的是修复受损心脏所需的全部吗?
Circ Res. 2013 Oct 12;113(9):1037-9. doi: 10.1161/CIRCRESAHA.113.302564.
6
Adult c-kit(pos) cardiac stem cells are necessary and sufficient for functional cardiac regeneration and repair.成体 c-kit(阳性)心脏干细胞对于功能性心脏再生和修复是必需且充分的。
Cell. 2013 Aug 15;154(4):827-42. doi: 10.1016/j.cell.2013.07.039.
7
c-Kit-mediated functional positioning of stem cells to their niches is essential for maintenance and regeneration of adult hematopoiesis.c-Kit 介导的干细胞功能定位到其龛位对于维持和再生成人造血至关重要。
PLoS One. 2011;6(10):e26918. doi: 10.1371/journal.pone.0026918. Epub 2011 Oct 26.
8
A model to study the phenotypic changes of interstitial cells of Cajal in gastrointestinal diseases.研究胃肠道疾病中 Cajal 间质细胞表型变化的模型。
Gastroenterology. 2010 Mar;138(3):1068-78.e1-2. doi: 10.1053/j.gastro.2009.11.007. Epub 2009 Nov 13.
9
A distant upstream locus control region is critical for expression of the Kit receptor gene in mast cells.一个远距离上游基因座控制区域对于肥大细胞中Kit受体基因的表达至关重要。
Mol Cell Biol. 2006 Aug;26(15):5850-60. doi: 10.1128/MCB.01854-05.
10
Correlation of murine embryonic stem cell gene expression profiles with functional measures of pluripotency.小鼠胚胎干细胞基因表达谱与多能性功能指标的相关性
Stem Cells. 2005 May;23(5):663-80. doi: 10.1634/stemcells.2004-0157.