Gradel Kim Oren, Schønheyder Henrik Carl, Arpi Magnus, Knudsen Jenny Dahl, Ostergaard Christian, Søgaard Mette
Center for Clinical Epidemiology, Odense University Hospital, Odense, Denmark ; Research Unit of Clinical Epidemiology, Institute of Clinical Research, University of Southern Denmark, Odense, Denmark.
Department of Clinical Microbiology, Aalborg University Hospital, Aalborg, Denmark ; Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.
Clin Epidemiol. 2014 Sep 18;6:301-8. doi: 10.2147/CLEP.S66998. eCollection 2014.
The Danish Collaborative Bacteraemia Network (DACOBAN) research database includes microbiological data obtained from positive blood cultures from a geographically and demographically well-defined population serviced by three clinical microbiology departments (1.7 million residents, 32% of the Danish population). The database also includes data on comorbidity from the Danish National Patient Registry, vital status from the Danish Civil Registration System, and clinical data on 31% of nonselected records in the database. Use of the unique civil registration number given to all Danish residents enables linkage to additional registries for specific research projects. The DACOBAN database is continuously updated, and it currently comprises 39,292 patients with 49,951 bacteremic episodes from 2000 through 2011. The database is part of an international network of population-based bacteremia registries from five developed countries on three continents. The main purpose of the DACOBAN database is to study surveillance, risk, and prognosis. Sex- and age-specific data on background populations enables the computation of incidence rates. In addition, the high number of patients facilitates studies of rare microorganisms. Thus far, studies on Staphylococcus aureus, enterococci, computer algorithms for the classification of bacteremic episodes, and prognosis and risk in relation to socioeconomic factors have been published.
丹麦菌血症协作网络(DACOBAN)研究数据库包含从三个临床微生物学部门服务的地理和人口统计学定义明确的人群的阳性血培养中获得的微生物学数据(170万居民,占丹麦人口的32%)。该数据库还包括来自丹麦国家患者登记处的合并症数据、丹麦民事登记系统的生命状态数据,以及数据库中31%未选定记录的临床数据。使用赋予所有丹麦居民的唯一民事登记号码能够与特定研究项目的其他登记处建立联系。DACOBAN数据库不断更新,目前包含2000年至2011年期间39292名患者的49951次菌血症发作。该数据库是来自三大洲五个发达国家的基于人群的菌血症登记国际网络的一部分。DACOBAN数据库的主要目的是研究监测、风险和预后。背景人群的性别和年龄特异性数据能够计算发病率。此外,大量患者便于对罕见微生物进行研究。迄今为止,关于金黄色葡萄球菌、肠球菌、菌血症发作分类的计算机算法以及与社会经济因素相关的预后和风险的研究已经发表。