Rybicki Frank J, Juan Yu-Hsiang, Saboo Sachin S, George Elizabeth, Bhivasankar Rani, Mitsouras Dimitrios
Applied Imaging Science Laboratory, Department of Radiology, Brigham and Women's Hospital & Harvard Medical School, 75 Francis Street, Boston, MA 02115.
Curr Cardiovasc Imaging Rep. 2014 Oct 1;7(10):9291. doi: 10.1007/s12410-014-9291-z.
Iodinated contrast delivery is a key component of coronary CT angiography. However, the purpose of contrast delivery has been limited to morphology alone. Specifically, iodine opacification of the coronary lumen has been used to separate it from the coronary artery wall and lesions within the coronary arteries. Because contrast is delivered to the coronary arteries according to the coronary blood flow, there is flow information encoded within the contrast opacification which, depending on CT hardware and acquisition protocol, can be recognized in coronary CT angiography. In addition, metrics related to flow have been identified and studied. They include coronary contrast opacification differences and contrast opacification gradients.
碘造影剂注入是冠状动脉CT血管造影的关键组成部分。然而，造影剂注入的目的一直仅限于单纯的形态学观察。具体而言，冠状动脉管腔的碘造影剂充盈已被用于将其与冠状动脉壁及冠状动脉内的病变区分开来。由于造影剂是根据冠状动脉血流注入冠状动脉的，因此在造影剂充盈中编码了血流信息，根据CT硬件和采集协议的不同，这些信息在冠状动脉CT血管造影中是可以识别的。此外，与血流相关的指标也已被确定并进行了研究。它们包括冠状动脉造影剂充盈差异和造影剂充盈梯度。
