Murphy Michele, Krothapalli Siva, Cuellar Jose, Kanjanauthai Somsupha, Heeke Brian, Gomadam Pallavi S, Guha Avirup, Barnes Vernon A, Litwin Sheldon E, Sharma Gyanendra K
Division of Cardiology, Medical College of Georgia, Georgia Regents University, 1120 15th Street, BBR 6518, Augusta, GA 30912-3105, USA.
J Obes. 2014;2014:419724. doi: 10.1155/2014/419724. Epub 2014 Aug 31.
Chest pain is a common problem in obese patients. Because of the body habitus, the results of noninvasive evaluation for CAD may be limited in this group.
We reviewed the records of 1446 consecutive patients who had undergone clinically indicated stress echocardiography (SE). We compared major adverse cardiac events (MACE; myocardial infarction, cardiac intervention, cardiac death, subsequent hospitalization for cardiac events, and emergency department visits) at 1 year in normal weight, overweight, and obese subjects with normal SE.
Excluding patients with an abnormal and indeterminate SE and those who were lost to follow-up, a retrospective analysis of 704 patients was performed. There were 366 obese patients (BMI ≥ 30), 196 overweight patients (BMI 25-29.9), and 142 patients with normal BMI (18.5-24.9). There was no MACE in the groups at 1-year follow-up after a normal SE.
In obese patients including those with multiple risk factors and symptoms concerning for cardiac ischemia, stress echocardiography is an effective and reliable noninvasive tool for identifying those with a low 1-year risk of cardiac events.
胸痛在肥胖患者中是一个常见问题。由于身体形态的原因，这组患者中冠心病的无创评估结果可能有限。
我们回顾了1446例连续接受临床指征的负荷超声心动图（SE）检查患者的记录。我们比较了体重正常、超重和肥胖且SE正常的受试者在1年时的主要不良心脏事件（MACE；心肌梗死、心脏介入治疗、心源性死亡、因心脏事件再次住院以及急诊就诊）情况。
排除SE异常且结果不确定的患者以及失访患者后，对704例患者进行了回顾性分析。其中有366例肥胖患者（BMI≥30），196例超重患者（BMI 25 - 29.9），142例BMI正常的患者（18.5 - 24.9）。SE正常的各组患者在1年随访时均未发生MACE。
对于包括有多种危险因素以及有心脏缺血相关症状的肥胖患者，负荷超声心动图是一种有效且可靠的无创工具，可用于识别1年内发生心脏事件风险较低的患者。
